小鼠肺中也有两类巨噬细胞,分为肺泡巨噬细胞(Alveolar macrophages)和肺间质巨噬细胞(Interstitial macrophages),可以用CD64+MerTK+圈出肺巨噬细胞,再通过CD11b和CD11c区分肺泡和肺间质巨噬细胞,且有利于在一个panel中同时做巨噬和...
Cleared aortas were immunostained with DAPI, and fluorescently labelled with antibodies to TSPO, the tissue resident macrophage marker F4/80 and the monocyte-derived macrophage marker CD11b. TSPO expression and the macrophage markers were visualised in fatty streaks and established plaques by light ...
Plausible explanations include CD11b-ICAM1 binding to divert CD11c-iC3b binding; CD11b occupying ICAM1 or ICAM2 sites on dendritic cells that block T-cell CD11a binding; and/or active signaling through macrophage CD11b. The relevance of anti-inflammatory pathways brought about by CD11b signaling...
蛋白别名:antigen CD11b (p170); macrophage antigen alpha polypeptide; integrin alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); leukocyte integrin alpha-M chain; Mac-1 alpha (Mac1A); MGC117044 基因别名:CD11B Entrez Gene ID:(Bovine) 407124 ...
44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Further, peritoneal macrophages are reported to express...
The characteristic DP Kupffer cells/Mφs that appeared in LH HFD mice did not express CRIg, which is a crucial marker for distinguishing the CD68+ resident Kupffer cells from recruited CD11b+ Kupffer cells/Mφs13,29. CD68+ Kupffer cells specifically express CRIg while recruited CD11b+ Kupffe...
(Fig.1dand Supplementary Fig.2b). These cells displayed low amounts of the macrophage markers, F4/80, CD88, and Siglec-F, but displayed high levels of Ly-6C (Fig.1e), a marker usually associated with inflammatory monocytes20. This display of Ly-6C allowed us to use flow cytometry to...
Cell Type Marker Glia marker Microglia marker Stem Cells Mesenchymal Stem Cells Negative Markers Stem Cells Hematopoietic Progenitors Hematopoietic Stem Cells Murine Lineage Negative Stem Cells Hematopoietic Progenitors Lymphoid B Lymphocytic Lineage Stem Cells ...
These Ly-6C+ cells had dendrites, lacked monocyte/macrophage markers such as F4/80 and CD115, and were absent in the mice lacking FMS-like tyrosine kinase 3ligand (FLT3L), a growth factor essential for cDC differentiation. Based on these observations, we conclude that this novel population ...
44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Further, peritoneal macrophages are reported to express higher lev...