Mesenteric lymph node CD11b(-) CD103(+) PD-L1(High) dendritic cells highly induce regulatory T cells. Immunology (2017) 152(1):52-64. doi:10.1111/imm.12747Shiokawa A, Kotaki R, Takano T, et al. Mesenteric lymph node CD11b- CD103+ PD-L1High dendritic cells highly induce ...
ARTICLES nature publishing group CD103 À CD11b þ dendritic cells regulate the sensitivity of CD4 T-cell responses to bacterial flagellin SM Atif1, S Uematsu2, S Akira2 and SJ McSorley1 Toll-like receptor 5 (TLR5) has been widely studied in an inflammatory context, but the effect of...
ARTICLES nature publishing group OPEN Intestinal CD103 þ CD11b À dendritic cells restrain colitis via IFN-g-induced anti-inflammatory response in epithelial cells ARBM Muzaki1,3, P Tetlak1,3, J Sheng1, SC Loh1, YA Setiagani1, M Poidinger2, F Zolezzi2, K Karjalainen1 and C Rue...
CD11b + CD103 - Sentinel DCs Relay a Tunable Antibacterial NFκB Response in Intestinal Epithelial Cells Via TNFIntestinal epithelial cell (IEC) NFκB signaling regulates the fine balance between mucosal homeostasis and inflammation. It is not fully understood which signal...
Additionally, we show the involvement of CD103+CD11b+ cDC2 in the induction of Th2-associated responses. CD11c-cre.Irf4fl/fl mice showed a reduced primary FliC-specific Th2-associated IgG1 responses, but enhanced Th1-associated IgG2c responses. These data expand our current understanding of ...
固有层(LP)在大量的吸收绒毛状上皮细胞之下,吸收细胞包含大量的树突状细胞(CD11c+CD11b+MHCII+cells)主要由CD103+CX3CR1- DCs两个组成,它能促进IgA生产、印在肠道淋巴细胞上和调节T细胞的发展。CX3CR1 +、CD103 -DCs(带有巨噬细胞的特征),促进肿瘤坏死因子(tnf- a)产生、结肠炎和T H17 T细胞的发展。
CD11b CD11c CD13 CD14 CD15 CD16 CD16·CD56 CD19 CD20 CD22 CD23 CD25 CD26 CD30 CD33 CD34 (Abnormal) CD34 (Progenitor) CD38+ / CD45+ CD38+ / CD45- CD41 CD45 CD56 CD57 CD58 CD61 CD64 CD71 CD79a CD103 CD117 CD138 cLambda FMC7 Granulocyte HLA·DR Kappa / CD19 Lambda / CD...
研究表明,用粒细胞巨噬细胞集落刺激因子(gm-csf)处理骨髓源单核细胞,可诱导获得单核源树突状细胞(modc);用fms样丝氨酸激酶3配体(fit3l)处理骨髓源常规样树突状前体细胞(pre-cdc),可以获得浆细胞样树突状细胞(pdc)、cd11b+cdc、cd24+cdc;如果用gm-csf和fit3l共同处理骨髓源pre-cdc,可以获得cd103+cdc。虽然...
CD103+CD11b+ dendritic cells (DCs) are unique to the intestine, but the factors governing their differentiation are unclear. Here we show that transforming growth factor receptor 1 (TGFβR1) has an indispensable, cell intrinsic role in the development of
Cancer remains one of the leading causes of mortality worldwide, leading to increased interest in utilizing immunotherapy strategies for better cancer treatments. In the past decade, CD103+ T cells have been associated with better clinical prognosis in p