Background Recently, human germinal center-associated lymphoma (HGAL) gene protein has been proposed as an adjunctive follicular marker to CD10 and BCL6. Methods Our aim was to evaluate immunoreactivity for HGAL in 82 cases of follicular lymphomas (FLs) - 67 nodal, 5 cutaneous and 10 ...
Programmed Death-1 (PD-1) is a Marker of Germinal Center-associated T Cells and Angioimmunoblastic T-Cell Lymphoma Shahsafaei A, Freeman GJ (2006) Programmed death-1 (PD-1) is a marker of germinal center-associated T cells and angioimmunoblastic T-cell lymphoma... DM Dorfman,JA Brown...
Given these premises, in this study, we investigated whether CD10 could represent a valid marker to discriminate mature neutrophils from immature neutrophil subsets under inflammatory conditions, and, if so, to eventually correlate its expression with cell-specific immunoregulatory properties. To address ...
Conclusion: The case we are intruducing here belongs to the rare subtype of follicular lymphoma which chracterized by MUM1(+) CD10(–) immunostaining marker. The pa-thology diagnosis is follicular lymphoma (MUM1(+) CD10(–)) (80%) with diffuse area(20%), degree: 3b. The progno-sis ...
摘要】目的探讨bcl 2、bcl 6、cd10在弥漫性大b细胞淋巴瘤(diffuselargeb celllymphoma,dlbcl)中的表达及意义。方法应用免疫组织化学sp法,检测60例弥漫性大b细胞淋巴瘤标本中bcl 2、bcl 6、cd10蛋白的表达水平。结果bcl 2、bcl 6、cd10在60例弥漫性大b细胞淋巴瘤中的表达率分别为55.0%(33/60)、48.3%(29/...
CD10 expression is reported to be a favorable prognostic marker for some tumors such as B-lymphoblastic leukemia/lymphoma, but unfavorable for others. Here, we report the case of a 33-year-old woman diagnosed with endometrial mixed carcinoma with the NEC component expressing CD10 who showed a ...
In DLBCL the expression was variable for both CD10 (21/54) and BCL-6 (39/47), with some tumors, including cases of transformed follicular lymphoma (9/10), coexpressing CD10 and BCL-6, and others expressing only BCL-6, and a small group expressing neither marker, possibly reflecting ...
Multivariate analysis revealed that Bcl-2 was the strongest prognostic marker followed by CD10 and MUM1. Stratification of patients according to a new algorithm based on expresJJF MurisDepartment of PathologyCJLM MeijerDepartment of PathologyW Vos...
Oncology NF-kappaB-dependent regulation of the diagnostic marker CD10 and role of BCL-2 activity in histone deacetylase inhibitor-induced apoptosis in human B-lymphoma cell lines BOSTON UNIVERSITY Thomas D. Gilmore ThompsonRyan CDiffuse large B-cell lymphoma (DLBCL) is a genetically heterogeneous ...
CD62L expression was significantly greater in CD5+ BCLL than in NHL (P <.001). Conversely, CD29, CD49d, and β7-integrin expression were significantly greater in NHL than in CD5+ BCLL (P <.001 for each marker). These differences persisted when only blood and bone marrow samples ...