蛋白别名: antigen CD11b (p170); CD11 antigen-like family member B; CD11b; Cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; CR-3 alpha chain; Integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); Leukocyte adhesion receptor...
Antigens, CD11BACKGROUND: Recent studies have raised the hypothesis that glucocorticoids could diminish the ability of endothelial cells to direct leukocyte traffic into inflamed tissues by inhibiting expression of the adhesion molecules endothelial-leukocyte adhesion molecule-1 and intercellular adhesion ...
蛋白别名: antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; Integrin alpha-L; integrin alphaL; integrin gene promoter; integrin, alpha L (antigen CD11A (...
宿主/亚型 Rabbit / IgG 种属反应性 human and More (2) 应用 WB, IHC, IF/ICC, ELISA and More (1) 别名 CD11b, CD11 antigen-like family member B, CR3A, CR-3 alpha chain, CR 3 alpha chain缓冲液配方: PBS and Azide PBS and Azide偶联物: Unconjugated Unconjugated...
High expression of CD11α has been associated with antigen-specific and tumor-reactive T cells (11,12). Hynes, R.O. (1992) Cell 69, 11-25. Ostermann, G. et al. (2002) Nat Immunol 3, 151-8. Fraemohs, L. et al. (2004) J Immunol 173, 6259-64. Swaim, C.D. et al. (20...
(ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood ...
(17). Other molecules participate in monocyte adherence, including very late antigen VLA-4 (a β1-integrin that interacts with vascular cell adhesion molecule type 1 [VCAM-1]) (18), and theselectinsystems (11,19). It has been shown that P-selectin (20) alone or in combination with E-...
What is the Cellular Role of the CD11 Protein? The CD11 protein is actually a heterodimer complex that consists of CD11b and CD18. CD11 is involved in numerous adhesion-related associations between cells such as monocytes, macrophages, natural killer (NK) cells, and granulocytes. CD11 also ...
能够激活初始T细胞的APC(Antigenpresenting cell)。CD11c被称为补体受体4(Complement receptor,CR4),是黏附分子CD11/CD18家族中的一 员,属于Ⅰ型跨膜糖蛋白,高表达于髓系DCs表 面 [1] 。CD11c作为一正性调控因子,参与DCs的黏 附、迁移,抗原的识别和呈递,并激活CD4 ...
viaTLR9(2). During an acute infection, high CD11b/Mac-1 expression on antigen-specificCD8(+)T cellscan signify recent activation of the immune system, whereas naive T cells and virus-specific memory CD8 (+) T cells express little or no Mac-1 when exposed to a virus (3). Variations at...