4. Lamark, T. and T. Johansen, Aggrephagy: Selective Disposal of Protein Aggregates by Macroautophagy. International Journal of Cell Biology, 2012. 2012: p. 736905.5. Scrivo, A., et al., Selective autophagy as a potential therapeutic target for neurodegenerative disorders. The Lancet Neurolo...
自噬(Autophagy)是细胞在面对内外不利环境时胞内形成的一种双层膜结构,其可将受损的细胞器、聚集体、外源致病菌等底物进行包裹并靶向运输到液泡/溶酶体中进行降解。因此,自噬对于细胞稳态的维持至关重要。根据降解底物的特异性可将...
自噬(Autophagy)是细胞在面对内外不利环境时胞内形成的一种双层膜结构,其可将受损的细胞器、聚集体、外源致病菌等底物进行包裹并靶向运输到液泡/溶酶体中进行降解。因此,自噬对于细胞稳态的维持至关重要。根据降解底物的特异性可将自噬分为选择性自噬和非选择自噬。聚集体自噬是一种特异降解蛋白聚集体的选择性自噬,其...
CCT2, traditionally viewed as a molecular chaperone, has emerged as a novel autophagy receptor that specifically targets solid protein aggregates for degradation. This ubiquitination-independent mode of recognition by CCT2 expands our understanding of protein degradation pathways. T...
Figure 2. Functional switch of CCT2 from a chaperonin subunit to an autophagy receptor Dr. Liang Ge (School of Life Sciences, Tsinghua University), Dr. Min Zhang (School of Pharmaceutical Sciences, Tsinghua University), ...
View Article human WB Autophagy Copper-dependent autophagic degradation of GPX4 drives ferroptosis Authors - Qian Xue View Article human WB Mol Cell Genome-scale exon perturbation screens uncover exons critical for cell fitness Authors - Mei-Sheng Xiao View Article See more citationsProteintech...
Autophagy related 5 Antibody hAPG5 Antibody Homolog of S Cerevisiae autophagy 5 Antibody OTTHUMP00000040507 Antibody Information: Target information shown above is from the UniProt Consortium. 产品留言 标题 联系人 联系电话 内容 验证码 点击换一张 注:1.可以使用快捷键Alt+S或Ctrl+Enter发送信...
Head and neck squamous cell carcinoma (HNSCC), a highly invasive malignancy with a poor prognosis, is one of the most common cancers globally. Circular RNAs (circRNAs) have become key regulators of human malignancies, but further studies are necessary to
4. Lamark, T. and T. Johansen, Aggrephagy: Selective Disposal of Protein Aggregates by Macroautophagy.International Journal of Cell Biology, 2012. 2012: p. 736905. 5. Scrivo, A., et al., Selective autophagy as a potential therapeutic target for neurodegenerative disorders.The Lancet Neurology...
5. Scrivo, A., et al., Selective autophagy as a potential therapeutic target for neurodegenerative disorders.The Lancet Neurology, 2018. 17(9): p. 802-815. 6. Kirkin, V., et al., A role for NBR1 in autophagosoma...