bone remodeling by three different processes such as; 1) osteoclastogenesis facilitated by positive-feedback loops of chemokines, 2) exerting osteolytic activity by CCR1 and CCR5, and 3) chemokine-mediated maturation of osteoblasts modulated positively by CCR1 and CCR5, and negatively by CX3CR1....
SummaryTwo chemokine (C-X3-C) receptor 1 (CX3CR1) gene polymorphisms, V249I and T280M, and 10 CC chemokine receptor 5 (CCR5) promoter haplotypes, P1–P10, have recently been reported to influence the progression of acquired immune-deficiency syndrome (AIDS). As these studies were performed...
Associations of fractalkine receptor (CX3CR1) and CCR5 gene variants with hypertension, diabetes and atherosclerosis in chronic renal failure patients unde... Associations of fractalkinereceptor (CX3CR1)and CCR5 gene variants with hypertension,diabetes and atherosclerosis in chronic renal failure patients...
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Suresh P, Wanchu A, Sachdeva RK, Bhatnagar A (2006) Gene polymorphisms in CCR5, CCR2, CX3CR1, SDF-1 and RANTES in exposed but uninfected partners of HIV-1 infected individuals in North India. J Clin Immunol 26:476–484Suresh P, Wanchu A, Bhatnagar A, Sachdeva RK, Sharma M (...
Autosomal recessive hypercholesterolemia is a rare inherited disorder, characterized by extremely high total and low-density lipoprotein cholesterol levels, that has been previously linked to mutations in LDLRAP1. We identified a family with autosomal recessive hypercholesterolemia not explained by mutations ...
目的:探讨靶向HIV-1细胞受体基因CCR5的不对称siRNA(asiRNA)在血清和动物体内的稳定性和在动物体内分布情况。方法:用内皮抑素同脂质胶束联合递送asiRNA,琼脂糖凝胶电泳法检测asiRNA的血清稳定性,ELISA法和活体荧光成像法检测asiRNA的体内分布。结果:改变合适的实验条件和asiRNA的修饰,可提高asiRNA的血清稳定性。用ELISA...
Gene polymorphisms in CCR5, CCR2, CX3CR1, SDF-1 and RANTES in exposed but uninfected partners of HIV-1 infected individuals in North India. Journal of clinical immunology. 2006; 26(5):476-84. https://doi.org/10.1007/s10875-006-9036-0 PMID: 16865553....
These data indicate that T-cell migration into human atherosclerotic plaques may predominantly occur via CCR5-CCL3 and CX3CR1-CX3CL1 interactions.doi:10.1002/eji.202049004Alexey KomissarovDaria PotashnikovaMichael L. FreemanVladimir Gontarenko
COMMON OR RARE GENETIC VARIATION IN THE CHEMOKINE RECEPTORS CCR2, CCR5, AND CX3CR1 DOES NOT RELATE TO CORONARY HEART DISEASE OR MYOCARDIAL INFARCTION IN HUMANSdoi:10.1016/s0735-1097(16)31892-7Golbus, Jessica R.Stitziel, NathanSamani, Nilesh...