1998年,国外,首次报道的抗环瓜氨酸肽抗体(anti-cyclic cirullinated peptide antibodies,抗CCP抗体)的检测,对RA具有较高的敏感性和特异性,是RA新的血清标志物。 ③那么抗ccp抗体到底为何物 抗环瓜氨酸肽抗体(anti-cyclic citrullinated peptide antibody, anti-ccp ...
就目前的数据来说,我们不能把抗CCP抗体作为判断诊类风湿关节炎患者的病情严重程度的指标。 引自:Porto LS, Tavares WC Júnior, Costa DA, Lanna CC, Kakehasi AM,Anti-CCPantibodies are not a marker of severity in established rheumatoidarthritis: a magnetic resonance imaging study. Rev BrasReumatol Engl...
Rabbit / IgG 分类 Polyclonal 类型 Antibody 抗原 Recombinant protein corresponding to Human CCP3. Recombinant protein control fragment (Product #RP-92759). 偶联物 Unconjugated 形式 Liquid 浓度 0.1 mg/mL 纯化类型 Antigen affinity chromatography
疫球蛋白 G(IgG)、免疫球蛋白 M(IgM)、免疫球蛋白 A(IgA)、肿胀关节计数、压痛关节计数均低于活动组,差异有统计学意义 (P<0.05)。结论通过血清抗 CCP 抗体、钙卫蛋白的变化可以判定类风湿关节炎患者的疾病程度 ,值得在临床中予以推广 使用。 关键词 类风湿关节炎;钙卫蛋白;血清抗 CCP 抗体 中图分类号 R59...
Anti-cyclic citrullinated peptide IgG antibodies (anti-CCP) are produced as an immune response in the presence of post-translational modified peptides known as cyclic citrullinated peptides (CCP). Anti-CCP have been considered as specific biomarkers for the diagnosis of rheumatoid arthritis (RA), ...
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类风湿性因子是血清学指标的一种,同时也是变 异性Fe段、IgG段为靶抗原的自身抗体,具有较高的敏 感性。同时由于敏感性相对较高,其在大多结缔组织病 变和慢性感染性疾病,甚至正常人体内均会呈现出一 定阳性率,对于类风湿性关节炎的诊断缺乏特异性, 会增加临床判断难度。积极探究更为有效的联合诊断 措施十分必要。
(本文编辑:杨林) 文章编号:1001-764X(2006)03-0205-01中图分类号:R446.6 文献标识码:B ·检验与临床· IgM、IgG、IgA类类风湿因子及抗CCP抗体对RA的诊断意义 张义东,董宇鸿(德清县人民医院检验科,浙江德清313200) 关键词:类风湿因子;抗环瓜氨酸肽抗体;类风湿性关节炎 蒙实验诊断有限公司,按试剂盒说明书操作...
The clinical sensitivity of IgG anti-CCP3 for the patients with CREST syndrome was 29% (15 of 52) and the specificity was 96% (384 of 397), with the exception of the RA group. The anti-centromere antibodies were significantly higher in patients with CREST only. The results of our study...
The EDIA™ anti-CCP test kit is an enzyme-linked immunosorbent assay (ELISA) for detection and semi-quantitation of IgG antibodies to Cyclic Citrullinated Peptides (CCP) in human serum or plasma. The assay is used to detect antibodies in a single specimen. The results of the assay are to...