关于抗环瓜氨酸肽抗体(anti-CCP antibody ),以下描述错误的是 A. 以IgG型为主的抗体 B. 可鉴别侵蚀性,非侵蚀性类风湿性关节炎 C. 特异性不如R
研究表明,Anti-CCP对关节的侵蚀性病变具有重要的预测价值,其阳性的未分化关节炎患者3年内进展为RA的概率可达90%,其原因可能与Anti-CCP参与疾病的致病过程有关[5]。 5、指导RA患者诊疗方案调整 研究表明,Anti-CCP阳性的RA患者相较阴性患者而言对甲氨蝶呤用药更为敏感,可为临床医师调整治疗方案和选择相应药物提供一...
Anti-cyclic citrullinated peptide IgG antibodies (anti-CCP) are produced as an immune response in the presence of post-translational modified peptides known as cyclic citrullinated peptides (CCP). Anti-CCP have been considered as specific biomarkers for the diagnosis of rheumatoid arthritis (RA), ...
IgA antibodies are the hallmark of mucosal immunity; the majority of saliva IgA antibodies are locally produced whereas IgG antibodies are largely serum derived(. Furthermore, IgA anti-CCP antibodies have recently been described in the sputum of at-risk individuals(. The relative importance of the...
The EDIA™ anti-CCP test kit is an enzyme-linked immunosorbent assay (ELISA) for detection and semi-quantitation of IgG antibodies to Cyclic Citrullinated Peptides (CCP) in human serum or plasma. The assay is used to detect antibodies in a single specimen. The results of the assay are to...
抗环瓜氨酸肽抗体(Anti-cyclic citrullinated peptide antibody, anti-CCP/ACPA)是类风湿性关节炎患者体内中出现的自身抗体,可在RA患者表现出临床典型症状前产生,传统RA相关自身抗体根据抗原的特性主要分为:以变性 IgG Fc 段为靶抗原的自身抗体RF,以瓜氨酸类蛋白为靶抗原的自身抗体anti-CCP及RA33抗体等。
human IgG, forming a complex when CCP‑specific antibodies are present in the sample. Calibrators ▪ 2nd incubation: After addition of streptavidin-coated microparticles, the Carefully dissolve the contents of one bottle by adding exactly 1.0 mL of complex becomes bound to the solid phase via ...
Anti-CCP antibodies (ACPA) have a high specificity and sensitivity for rheumatoid arthritis (RA). They belong to the IgG class and have more than 56% sensitivity and more than 90% specificity for RA, depending on the assay kit used. They are directed against peptides and proteins, which ...
AB0265 The significance of early diagnosis and prognostic evaluation of four kinds of ANTI-CCP antibodies in various types of juvenile idiopathic arthritis ObjectivesTo investigate the relationship between immunological parameters AKA, anti - CCP, the RF- IGG, RF-IGM and the early diagnosis and pr...
Anti-CCP antibodies in children with Juvenile Idiopathic Arthritis (JIA) - Diagnostic and clinical significance Anti-cyclic citrullinated peptide (anti-CCP) antibodies are considered to be a marker of rheumatoid arthritis (RA). However, limited and controversial reports concern this problem in children...