We found that CD4+ T cells could activate P-STAT3 signaling via secreting CCL5 and adding a STAT3 inhibitor can reverse the chemoresistance. In vivo mouse model with xenografted 22RV1 cells and CD4+ T cells also confirmed the in vitro results. Conclusions Together, our results indicate that ...
FAQ COA 已发表文献 RANTES is a CC chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain st...
RANTES is a CC chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HI...
(5,863.3–15,769.5) 0.01 Nasopharyngeal IL-6 291.7 (152.0–522.1) 335.1 (229.7–368.8) 0.03 NK cells 0.12 (0.06–0.27) 0.41 (0.20–0.58) <0.01 CD4+ T cells 1.67 (1.24–2.25) 2.80 (2.32–3.56) <0.01 CD4/CD8 ratio 2.60 (2.60–3.78) 5.28 (3.31–7.91) 0.01 Numbers are presented as ...
价格:33030 货号:AF-300-06-1000 规格:1mg 价格:50820 产品介绍 技术参数 相关产品 产品介绍 产品描述: RANTES is a CC chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO)...
Murine C10 belongs to the CC chemokine family and is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL-3 or IL-4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits...
A CD4 + T cell antagonist epitope down-regulates activating signaling proteins, up-regulates inhibitory signaling proteins and abrogates HIV-specific T cel... CD4+ T cells are critically important in HIV infection, being both the primary cells infected by HIV and likely playing a direct or indire...
'People living with HIV-1 and HTLV-2 concomitantly show slower CD4+ T cell depletion and AIDS progression, more frequency of the natural control of HIV-1, and lower mortality rates. A similar beneficial effect of this infection has been reported on HCV coinfection reducing transaminases, increas...
因此,ccl5抗体或ccl5受体拮抗剂被认为可能作为治疗艾滋病的一种新途径(nct01428986 safety study of maraviroc's effecton human osteoclasts;nct03666871 ccr5-modified cd4+t cells for hivinfection)。3、自身免疫疾病是免疫系统攻击自身组织的疾病。研究表明,ccl5在多种自身免疫疾病中发挥作用,例如类风湿性关节炎(...
and CCL5 and the selected cytokines IL-3, IL-4, and IFNgamma in supernatants of in vitro-stimulated CD4 + and CD8 + T cells at 5 days after stimulation. A summary of three independent measurements on three mice (with their genotypes indicated) are shown. Error bars indicate Mean...View...