Essential cytokines implicated in this process comprise interleukins (e.g., IL-1β, IL-6, IL-8), tumor necrosis factor-alpha (TNF-α), and chemokines such as CCL2, CXCL10, and CCL3. These chemicals enhance the inflammatory response by facilitating additional recruitment of immune cells to...
factor and TNF-alpha in the sequestration of neutrophils in the lung: effects on neutrophil deformability, adhesion receptor expression, and chemotaxis. Europe... Drost, Ellen M.,W Macnee - 《European Journal of Immunology》 被引量: 86发表: 2015年 Effects of inhibitors of the chemokine recep...
Mesenchymal stromal cells (MSC) have immunomodulatory effects impacting macrophages, promoting polarisation towards a reparative phenotype. CCL2 is a potent cytokine involved in the recruitment of macrophages. We hypothesised that MSC derived CCL2 may be
TNF-alpha-induced chemokine production and apoptosis in human neural precursor cells J Leukoc Biol, 78 (2005), pp. 1233-1241 CrossrefView in ScopusGoogle Scholar 26 V Waetzig, K Czeloth, U Hidding, K Mielke, M Kanzow, S Brecht, M Goetz, R Lucius, T Herdegen, UK Hanisch c-Jun N...
Monocyte chemoattractant protein (CCL2/MCP-1) is a chemokine that attracts cells involved in the immune/inflammatory response. As microglia are one of the main cell types sustaining inflammation in brain, we proposed here to analyze the direct effects of
Molecular mechanisms of syndecan-4 upregulation by TNF-alpha in the endothelium-like EAhy926 cells J Biochem, 154 (2013), pp. 41-50 Google Scholar [39] F Charni, V Friand, O Haddad, H Hlawaty, L Martin, R Vassy, O Oudar, L Gattegno, N Charnaux, A Sutton Syndecan-1 and syndeca...
CCL2 increases the levels of secreted pro-inflammatory cytokines and chemokines through its interaction with CCR2 receptor and subsequent downstream signaling pathway effects such as, but not limited to: IL-1 beta, TNF-alpha, IL-6, and IFN-gamma. These increased pro-inflammatory cytokines and che...
TNF-Alpha Promotes an Inflammatory Mammary Microenvironment That Favors Macrophage and Epithelial Migration in a CCL2- and Mitochondrial-ROS-Dependent MannerTUMOR necrosis factorsADIPOSE tissue physiologyMACROPHAGESEPITHELIAL cellsCANCER cellsINFLAMMATORY mediators...
Well-characterized exerkines include interleukin 1-beta (IL-1B), interleukin 6 (IL-6), and tumor necrosis factor alpha (TNF-a); these are known pro-inflammatory cytokines and are released in the early stages of inflammation [17,19]. Interleukin 10 (IL-10) is an anti-inflammatory ...
An evolutionarily conserved TNF-alpha-responsive enhancer in the far upstream region of human CCL2 locus influences its gene expression. J. Immunol. 186, 7025–7038 (2011). 35. van Lint, A.L. et al. Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent ...