Gene ID: 868 种属 Homo sapiens 基因DNA序列编号: NM_001321786.1 基因DNA描述 Homo sapiens Cbl proto-oncogene B (CBLB), transcript variant 1, mRNA DNA编码区: atgggctatttgtgtgttaatttcatttggttcttgggaataacgactcaccgcgttgat ttaaagaaagaactaaaattccagatggcaaactcaatgaatggcagaaaccctggtggt cgaggaggaaatccc...
基因检测报告英文版基因简介 This gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell re...
Gene SummaryThis gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell...
Kosoy R, Yokoi N, Seino S, Concannon P: Polymorphic variation in the CBLB gene in human type 1 diabetes. Genes Immun 2004, 5:232-235.Kosoy R, Yokoi N, Seino S, Concannon P. Polymorphic variation in the CBLB gene in human type 1 diabetes. Genes Immun 2004;5:232-5....
Studies in mouse suggest that this gene is involved in antifungal host defense and that its inhibition leads to increased fungal killing. Manipulation of this gene may be beneficial in implementing immunotherapies for a variety of conditions, including cancer, autoimmune diseases, allergies, and ...
Gene SummaryThis gene encodes an E3 ubiquitin-protein ligase which promotes proteosome-mediated protein degradation by transferring ubiquitin from an E2 ubiquitin-conjugating enzyme to a substrate. The encoded protein is involved in the regulation of immune response by limiting T-cell receptor, B-cell...
基因基本信息 基因名称 Cblb Gene ID 208650 品系名称 遗传背景 C57BL/6J 修饰方式 CKO 应用领域 表型 靶向缺失突变的纯合子显示T细胞产生的il - 2升高,形成自发的自身免疫,并且对实验性自身免疫性脑脊髓炎高度敏感。 品系状态 冷冻 目录号 VSM4101152 返回列表 返回...
CBLB (Cbl Proto-Oncogene B) is a Protein Coding gene. Among its related pathways are Chronic myeloid leukemia and Pathways in cancer. GO annotations related to this gene include calcium ion binding and ubiquitin-protein transferase activity. An important paralog of this gene is CBL. ...
Gene Name CBLB Accession No. Q13191 Alternate Names AI429560; AI851073; Cas Br M (murine) ecotropic retroviral transforming sequence b; Casitas B lineage lymphoma b; Casitas B lineage lymphoma proto oncogene b; Casitas B-lineage lymphoma proto-oncogene b; Cbl b; CBLB; CBLB_HUMAN; DKFZp686...
关键词: Multiple sclerosis TYK2 CBLB LMP7 Gene Interferon-beta DOI: 10.1016/j.jneuroim.2017.11.004 年份: 2020 收藏 引用 批量引用 报错 分享 全部来源 求助全文 万方 相似文献Down-regulation of TYK2, CBLB and LMP7 genes expression in relapsing-remitting multiple sclerosis patients treated with ...