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The Transcription Factors T-bet and Runx Are Required for the Ontogeny of Pathogenic Interferon-γ-Producing T Helper 17 Cells Summary T helper 17 (Th17) cells can give rise to interleukin-17A (IL-17A)- and interferon (IFN)-γ-double-producing cells that are implicated in developme... Yan...
T-bet (encoded by Tbx21) is a key transcription factor to regulate iNKT1 cell differentiation27. Interestingly, we did not observe obvious Tbx21 expression in any clusters or open regions near Tbx21 in ST0 iNKTp (data not shown). Overall, our pseudotime-based analysis of developmental ...
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