Region between residue 166 and 187 of human Core-Binding Factor, Beta Subunit. 偶联物 Unconjugated 形式 Liquid 浓度 1 mg/mL 纯化类型 Antigen affinity chromatography 保存液 phosphate/tris citrate, pH 7-8 内含物 0.09% sodium azide 保存条件 ...
CBFB 基因简介 中英文全称:核心结合因子, β 亚基 core-binding factor, beta subunit 分布:核 活性:转录因子|RNA聚合酶II 转录因子|转录辅 激活蛋白 参与:转录自RNA聚合酶II 启动子 病变:髓性 白血病, 急性, M4Eo 亚型 OMIM/位置:121360 16q22.1
Background: Core binding factor beta (CBFβ) is a binding partner to the RUNX family of DNA binding transcription factors (RUNX1-3) and acts as a transcriptional co-activator by allosterically increasing their affinity for DNA. RUNX2 is the master regulator of bone growth and differentiation, ...
英文名称:Recombinant Core Binding Factor Beta Subunit (CBFb) 保质期:避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。 保存条件:2-8°C不超过一个月,-80°C不超过12个月 核心结合因子β亚基(CBFβ)重组蛋白的产生是应用了重组DNA或重组RNA的技术从而获得的蛋白质。目前,体外重组蛋白的生产主要...
Runx proteins heterodimerize with another protein commonly referred to as core binding factor beta (CBFβ), a non-DNA binding protein that allosterically enhances the DNA binding of the Runt domain [9]. Mammalian CBFβ also increases the half-life of Runx1 by protecting it from ubiquitin-mediat...
CBF-β/CBF: Beta core binding factor beta Cul5: Cullin5 EB/EloB: ElonginB EBΔC34: ElonginB mutant with a deletion of the 34 amino acids in the C-terminal tail EC/EloC: ElonginC HIV-1: Human immunodeficiency virus type 1 mAb: Monoclonal antibody ...
Total RNA from HoxB4 cells transfected with empty vector (control), AE9a or AE9aNT was reverse transcribed in cDNA and analyzed via qPCR. Data were normalized to the housekeeping gene TATA-binding protein. The mean ± SD of triplicate experiments is shown (nsNot significant, *P<0.05, ...
RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human CBFB (core-binding factor subunit beta...
Core-binding factors-beta (CBFβ) is a non-DNA-binding factor that combines with the runt-related transcription factor family transcription factors to mediate their DNA-binding affinities, and plays a critical role in regulating osteogenic differentiation. In this study, we explored the mechanisms ...
The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates. Mol Cell Biol. 1998;18:7432–43. Article CAS PubMed PubMed Central Google Scholar Lutterbach B, Hou Y, Durst KL, Hiebert SW. The inv(...