CBFB 基因简介 中英文全称:核心结合因子, β 亚基 core-binding factor, beta subunit 分布:核 活性:转录因子|RNA聚合酶II 转录因子|转录辅 激活蛋白 参与:转录自RNA聚合酶II 启动子 病变:髓性 白血病, 急性, M4Eo 亚型 OMIM/位置:121360 16q22.1
英文名称:Recombinant Core Binding Factor Beta Subunit (CBFb) 保质期:避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月。 保存条件:2-8°C不超过一个月,-80°C不超过12个月 核心结合因子β亚基(CBFβ)重组蛋白的产生是应用了重组DNA或重组RNA的技术从而获得的蛋白质。目前,体外重组蛋白的生产主要...
背景资料Core-binding factor subunit beta is a protein that in humans is encoded by the CBFB gene.The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of gene...
RNA InterferenceCore Binding Factor beta SubunitCell Line, TumorNeoplasm InvasivenessFemalep pBackground/p pThe transcription factor Runx2 has an established role in cancers that metastasize to bone. In metastatic breast cancer cells Runx2 is overexpressed and contributes to the invasive capacity of ...
two subunits, alpha and beta, in which the alpha subunit binds to DNA and is encoded by one of the RUNX1 (AML1, CBFa2), RUNX2 (CBFa1) and RUNX3 (CBFa3) genes, whereas the beta subunit (CBFb) is thought not to bind to DNA but to stabilize the DNA binding of the alpha ...
For the in vitro quantitative measurement of Human Core-binding factor subunit beta (CBFB) concentrations in tissue homogenates, cell lysates and other biological fluids.产品特点 Human Core-binding factor subunit beta (CBFB) ELISA Kit检测范围:0.156 ng/ml - 10 ng/ml保存建议 4℃下运输。收到该Hu...
上海玉博生物科技有限公司 主要致力于“Human CBF beta (residues 1-20) Synthetic Peptide Pierce-PEP282”的生产销售。多年的“Human CBF beta (residues 1-20) Synthetic Peptide Pierce-PEP282”生产与销售的经验,与各行业新老用户建立了稳定的合作关系,我公司经营的
Gene Summary Contributes to sequence-specific DNA binding activity. Involved in negative regulation of CD4-positive, alpha-beta T cell differentiation; negative regulation of transcription by RNA polymerase II; and positive regulation of CD8-positive, alpha-beta T cell differentiation. Acts upstream of...
However, there was still significant CBFβ-induced suppression of HBV replication in pHBV1.2ΔX-transfected HepG2 cells; CBFβ is the beta subunit of a heterodimeric core-binding transcription factor, suggesting that there might be a HBx-independent mechanism for CBFβ suppres- sion of HBV ...
Besides previously validated genes, DUSP4, DET1, and COP1, we also identified in the same genetic screen RUNX2 (formerly known as core-binding factor subunit alpha-1 or CBFA1) and its transcriptional coactivator; CBFB (core-binding factor subunit beta) as regulators of the MEK inhibitor ...