We hypothesized that children with mild CK elevation and no weakness would be unlikely to have neuromuscular disorders and require additional evaluation. Methods: We retrospectively evaluated patients between 1 and 18 years of age seen at a single children's hospital over a 3-calendar-year period ...
A sigmoidal survival-BOP dose-response curve was obtained which was then used to delineate the upper threshold of mild TBI based on the logistic regression model. We then carefully examined this range using other potential indicators of injury. This range was found to compromise the integrity of ...
For example, a sudden onset of general symptoms, such as weight loss or feeling generally ill, is usually taken to mean that the course of sarcoidosis will be relatively short and mild. Dyspnea and possibly skin sarcoidosis often indicate that the sarcoidosis will be more chronic and severe. ...
54. Creatine kinase maintains energetics by rapidly and reversibly transferring a high-energy phosphoryl moiety between ATP and creatine phosphate, a highly diffusible high-energy phosphate molecule important for cellular energy homeostasis. Overexpression of CK-M, the...
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Using a combination of corneal crosslinking and Intacs implants also has demonstrated promising results for treating keratoconus. Also, progressive mild to moderate keratoconus has been safely and successfully treated with a combination of corneal crosslinking and implantation of a toricphakic IOL. ...
Genotype-phenotype associations from GWAS and family studies indicated that common and rare variants in candidate genes are related to mild and severe HTG [16, 20–22]. On the other hand, homozygosity mapping is a straightforward approach based on linkage analysis suitable for the study of ...
decreased by stretching the arch. Generally, in mild cases of plantar fasciitis, the pain will decrease as the soft tissues of the foot "warm up"; however, pain may increase as the use of the foot increases. In more severe cases of plantar fasciitis, pain may increase when the arch is ...
Major eruptions can thus introduce a double jeopardy of marked coldness and drought during the agricultural growing season. The resulting impacts may be compounded by livestock death, accelerated land degradation, and additional crop damage from the survival of agricultural pests during regionally mild ...
While these irradiated mice did not develop perivascular fibrosis, their lungs did develop mild parenchymal fibrosis when subsequently challenged by hypoxia (Supplementary Fig. 26). In another model of human disease, we found significantly higher levels of Thbs1 mRNA and a strong trend (P ¼ ...