High triglycerides along with poor cholesterol may also affect your kidneys. A 2016 study published in theJournal of Clinical Medicinehas found that elevated triglycerides and low HDL cholesterol may cause kidney issues(4). High triglycerides may also increase the risk of heart disease. A 2018 stud...
The prevalence of obesity/elevated BMI increased with age; BMI was generally reported within the normal range until age of 4 years and rose significantly thereafter. The identified truncating SPEN variants were distributed throughout the coding region of the gene. A comparison of the clinical ...
elevated iron levels occur due to groundwater lowering caused by agricultural drainage or by the entry of iron-containing groundwater into streams [55]. Iron hydroxide deposition can cause both direct (e.g., toxic effects, gill sticking) and indirect effects...
Elevated amygdala response to faces and gaze aversion in autism spectrum disorder. Soc Cogn Affect Neurosci 9: 106–117. Unger EK, Burke KJJ, Yang CF, Bender KJ, Fuller PM, Shah NM (2015). Medial amygdalar aromatase neurons regulate aggression in both sexes. Cell Rep 10: 453–462. van ...
The detrimental effects of elevated APP-CTFs herein underscore their significance as a therapeutic target to address AD progression at an early stage, preceding the appearance of amyloid plaques. Results Inhibition of γ-secretase induces lysosomal dysfunction prior to affecting endosomes To address the ...
Here, we reveal an effective PAR accumulation that coincides with elevated γH2AX following treatment with a novel PARGi in PC3 cells that have intact BRCA1 and BRCA2 genes42. Fig. 5 PARGi sensitizes cells to IR damage. a High level of PAR accumulation and γH2AX foci formation in cells ...
It is worth mentioning that the mother and the sister of the proband showed elevated levels of Apo C-II and Apo C-III. Genome scan Genomic DNA from saliva was checked for integrity, treated with RNAse and fluorometrically quantified (Qubit platform, Invitrogen). A genome-wide scan for ...
of mitochondrial dNTPs in Mpv17-/- liver slows the DNA replication in the organelle, as evidenced by the elevated level of replication intermediates. Quiescent fibroblasts of MPV17-mutant patients recapitulate key features of the primary affected tissue of the Mpv17-/- mice, displaying virtual ...
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Elevated muscle enzyme levels likely resulted from muscle distress rather than from dehydration.Makoto Ide and Fumihiro Tajima and Kazunari Furusawa and Takashi Mizushima and Hajime OgataArchives of Physical Medicine and RehabilitationIde M, Tajima F, Furusawa K et al (1999) Wheelchair marathon racing ...