Disorders with an enlarged spleen (splenomegaly), such as lymphoma, leukemia, infectious mononucleosis, malaria, toxoplasmosis, liver cirrhosis, sarcoidosis, rheumatoid arthritis, systemic lupus erythematosus, sickle cell anemia and hemolytic anemia, may cause mild discomfort or sensation of fullness rather...
A spleen is normally about the size of your fist. A doctor usually can't feel it during an exam. But infections and injuries can cause it to swell and become larger. Many health conditions can cause an enlarged spleen (splenomegaly). Your doctor will need to do examinations to figure out...
Treatment with JAK inhibitors (JAKi) have lead to marked improvement in symptoms and splenomegaly. Signaling through the JAK pathway is critical for T cell development and differentiation. However the baseline immune signature remains largely undescribed in MPN as does the effect of JAK inhibition on...
it tries to bypass the portal system, using the systemic venous system to return to the heart. Symptoms of portal hypertension are due to the complications of decreased blood flow through the liver and from increased pressure within the veins where...
Cirrhosis is a complication of liver disease that involves the loss of liver cells. Learn about causes, treatment, symptoms, stages, life expectancy, and more.
When both, your liver and your spleen become enlarged, it is a condition known as hepatosplenomegaly. But there is a little bit more to this condition than just the symptoms of it. If left unchecked, it can lead to serious medical issues.It is not someth
Acute.Acute abdominal pain starts over a few hours or days and may come with other symptoms. It’s pretty common and rarely much of a concern. It could be gas, for example. But if you have severe pain that comes on suddenly, you’re more likely to have something more serious that mig...
Paleness or yellowness of skin Tachycardia, or abnormally fast heart rate Changes in the eyes Elevated body temperature Enlarged spleen (Splenomegaly) Patients are likely to exhibit even more symptoms. Based on the severity of the disorder, they may also experience pinpricks and loss of temperature...
Acute.Acute abdominal pain starts over a few hours or days and may come with other symptoms. It’s pretty common and rarely much of a concern. It could be gas, for example. But if you have severe pain that comes on suddenly, you’re more likely to have something more serious that mig...
Treatment of primary biliary cirrhosis has the following objectives: to alleviate symptoms, to slow the immune process and disease progression. Ursodeoxycholic acid (UDCA) is very effective, especially in the early stages of primitive biliary cirrhosis. This drug is administered lifelong and studies ...