Cationic host defense (antimicrobial) peptides. Curr. Opin. Immunol. 2006, 18, 24-30. [CrossRef] [PubMed]Brown, K. L., and Hancock, R. E. W. (2006) Cationic host defense (antimicrobial) peptides. Curr. Opin. Immunol. 18, 24-30....
Cationic host defense (antimicrobial) peptides were originally studied for their direct antimicrobial activities. They have since been found to exhibit multifaceted immunomodulatory activities, including profound anti-infective and selective anti-inflammatory properties, as well as adjuvant and wound-healing ...
Cationic host defense (antimicrobial) peptides were originally studied for their direct antimicrobial activities. They have since been found to exhibit multifaceted immunomodulatory activities, including profound anti-infective and selective anti-inflammatory properties, as well as adjuvant and wound-healing ...
The advantages of these CAPs are that (i) they are highly selective against the negatively charged bacterial membrane versus the zwitterionic mammalian membranes of a human host and that (ii) there is no specificity in targeting, as the peptides function by physically disrupting the bacterial ...
variety of harmful microbes in the surrounding environment, particularly at high densities (of which intensive farming represents an extreme example), shrimps have evolved and use a diverse array of antimicrobial peptides (AMPs) as part of an important first-line response of the host defense system...
Host defense peptideplasma cell myelomacytolysisDNA fragmentationMultiple myeloma is a common hematological malignancy that urgently requires new approaches to treatment, since the disease is not curable using current chemotherapeutic regimens. The aim of this study was to determine whether human and mouse...
Generation of novel cationic antimicrobial peptides from natural non-antimicrobial sequences by acid-amide substitution - Ueno, Masaomi, et al. () Citation Context ... cationic antimicrobial peptides are produced by higher metazoans as host defense against microorganisms [14]. Recently they have ...
cationic peptides are highly effective against drug-resistant Gram-negative pathogens5,6,7,8,9. In the past four decades, thousands of cationic peptides with broad antimicrobial activities have been identified with most of them being either natural or naturally-derived host–defense peptides from ...
The prominent sequence and structural similarity of this anti-inflammatory peptide with CAMPs was implicated towards its role in host defense18. Cutuli et al. first established direct in vitro antimicrobial effect of α-MSH and its carboxy-terminal tripeptide α-MSH(11–13) against Candida albicans...
determine the antimicrobial activity of cationic IDPs. Hence, we propose to name them “Cationic Intrinsically Disordered Antimicrobial Peptides, CIDAMP”. If cationic IDP or “Intrinsically Disordered Protein Regions (IDPR)” of various origins, containing a high percentage of distinct disorder-promoti...