Synonyms OSIL antibody; Oxidative stress induced like antibody p60 antibody p62 antibody p62B antibody Paget disease of bone 3 antibody PDB 3 antibody PDB3 antibody Category Autophagy Background Sequestosome 1 (SQSTM1, p62) is a ubiquitin binding protein involved in cell signaling, oxidative stress...
In this paper, we studied the interaction of 1,2,4-Oxadiazoles derivatives with anticancer drug target enzymes (PDB ID 3SRC).Kashaw, Sushil K.Dr Hari Singh Gour VishwavidyalayaAgarwal, ShivangiWayne State UnivMishra, MitaliSau, SamareshIyer, Arun K....
Positions of the Met residues are denoted in the caspase-3 structure (PDB code: 1I3O33). To generate this structure, the active site (Cys-163) of recombinant procaspase-3 was mutated to Ala, and the protein was digested by granzyme and cocrystallized with XIAP. The N-terminal 1–31 ...
通过RCSB Protein Data Bank数据库(https://www.rcsb.org/)查找Caspase-1/GSDMD/NRP3蛋白的晶体结构,筛选条件物种设置为人类,蛋白-配体复合物分辨率低于0.3 nm,将选中的蛋白-配体晶体机构下载保存。利用PyMOL软件对蛋白质进行去水、去...
Additional File 1: ZIP file is a pdb format that is compressed. It contains caspase-3/peptide complexes (casp3_pep.pdb), caspase-7/peptide complexes (casp7_pep.pdb), caspase-8/peptide complexes (casp8_pep.pdb), and caspase-9/peptide complexes (casp9_pep.pdb). (ZIP 143 KB) ...
The α-asarone compound was obtained from the PubChem web-database and the biological target compound α-asarone was obtained from the web protein database (RCSB PDB) is Caspase-3 (CASP-3). Prediction of biological activity using Pass Online. The interaction of α-asarone compounds with ...
首先从蛋白质结构数据库(protein data bank,PDB)数据库(https: //www.rcsb.org)中检索关键靶点蛋白信息,根据蛋白结构的分辨率、完整性、结合口袋的形状、大小和化学性质以及蛋白结构的共晶配体等相关信息,确定蛋白结构。利用PyMOL软件去除...
The Protein Data Bank (PDB; http://www.rcsb.org/pdb/ ) is the single worldwide archive of structural data of biological macromolecules. This paper describes the goals of the PDB, the systems in place for data deposition and access, how to obtain further information, and near-term plans fo...
The PDB format of NLRP3 (ID: 6npy) [14] was downloaded from RCSB (https://www.rcsb.org/), waters and het groups were deleted, and hydrogens were added, and then the docking procedure was submitted [15]. 2.2. Animals Male Sprague-Dawley (SD) rats were purchased from Pizhou Oriental...
Three-dimensional crystal structure was retrieved from PDB database. This structure was optimized prior to docking using the Protein Preparation Wizard in Schrodinger Maestro11.0. Inconsistencies in the structure such as missing hydrogen, incorrect bond orders, orientation of the different functional groups...