caspase-independentautophagyprogrammed cell deathcathepsinlysosomesproteasomeCaspase activation has been frequently viewed as synonymous with apoptotic cell death; however, caspases can also contribute to processes that do not culminate in cell demise. Moreover, inhibition of caspases can have cytoprotective ...
T lymphocyte death is essential for proper function of the immune system. During the decline of an immune response, most of the activated T cells die. Cell death is also responsible for eliminating autoreactive lymphocytes. Although recent studies have f
Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells. Purpose: Results of multiple clinical trials suggest that EGF receptor (EGFR) tyrosine kinase inhibitors (TKI) exhibit negative effects on platinum-based c....
Caspase-independentCellDeath SONGBai-fen,CUIYu-dong,CAOHong-wei (AnimalscienceandTechnologyCollegeofHeilongjiangAugustfirstAgriculturalReclamationUniversity,DaqinHei- longjiang163319) Abstract:Apoptosisisaphysiologicalcelldeathmechanism,itiscellsuicidecontrolledbypolygene.Ingeneral,apop- ...
Caspase independent cell death : leaving the set without the final cut S Tait - 《Oncogene》 被引量: 0发表: 2008年 The GPI Transamidase Complex of Saccharomyces cerevisiae Contains Gaa1p, Gpi8p, and Gpi16p Gpi8p and Gaa1p are essential components of the GPI transamidase that adds glycosyl...
Both caspase-dependent and caspase-independent cell death executors participate in yeast cell death. On one hand, a yeast caspase-like protease appears to be essential for approximately 40% of the investigated cell death scenarios. On the other hand, factors like the mitochondrially located ...
Cell Death Differ. 10: 798-807Yanagisawa, H., Miyashita, T., Nakano, Y., and Yamamoto, D. (2003). HSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase- independent autophagic cell death. Cell Death Differ. 10, 798-807....
Geranylgeraniol, an Intermediate Product in Mevalonate Pathway, Induces Apoptotic Cell Death in Human Hepatoma Cells: Death Receptor-independent Activation... induces apoptotic cell death in human hepatoma cells: death receptor-independent activation of caspase-8 with down-regulation of Bcl-xL expression....
PML induces a novel caspase-independent death process.PML nuclear bodies (NBs) are nuclear matrix-associated structures altered by viruses and oncogenes. We show here that PML overexpression induces rapid cell death, independent of de novo transcription and cell cycling. PML death involves cytoplasmic...
PML induces a novel caspase-independent death process. Nat Genet 20: 259-265, 1998.Quignon, F., DeBels, F., Koken, M., Feunteun, J., Ameisen, J.C., and de The, H. (1998). PML induces a novel caspase-independent death process. Nat. Genet. 20, 259 -265....