Imaging articular cartilage has become one of the most dynamic areas of development in musculoskeletal radiology, and over the past several years numerous advances have been made in both in vitro and in vivo imaging of this tissue. Yet, integrating these techniques into epidemiological studies and ...
椎间盘主要由三种类型的组织组成:髓核、纤维环和终板。髓核细胞功能异常被认为是IDD的关键因素,细胞衰老是髓核细胞功能异常的主要原因。 2021年3月1日,骨科实验室在Osteoarthritis & Cartilage杂志上发表题为Senolytic agent Quercetin ameliorat...
The cellular and molecular mechanisms responsible for the initiation and progression of osteoarthritis (OA), and in particular cartilage degeneration in OA, are not completely understood. Increasing evidence implicates developmental processes in OA etiology and pathogenesis. Herein, we review this evidence....
Despite the increasing interest in using knee cartilage volume as an outcome measure in studies of osteoarthritis (OA), it is unclear what components of knee cartilage will be most useful as markers of structure in the tibiofemoral (TF) joint. To compare the changes that occur in femoral and ...
P366 CARTILAGE CHANGES IN PATIENTS WITH OSTEOARTHRITIS AFTER HIGH TIBIAL OSTEOTOMYP366 CARTILAGE CHANGES IN PATIENTS WITH OSTEOARTHRITIS AFTER HIGH TIBIAL OSTEOTOMYdoi:10.1016/S1063-4584(07)60812-7B.VanwanseeleandU.ArnetandD.ParkerandM.SDOSOsteoarthritis & Cartilage...
In this Review, the authors summarize the changes that occur in the biocomposite formed by articular cartilage and bone during the evolution of osteoarthritis (OA). They also discuss how an improved understanding of these changes could be exploited to de
Changes in the osteochondral unit during osteoarthritis: structure, function and cartilage-bone crosstalk. In diarthrodial joints, the articular cartilage, calcified cartilage, and subchondral cortical and trabecular bone form a biocomposite - referred to as the... Goldring,Steven,R.,... - 《Nature...
In conclusion, the results in this thesis support the idea that OA is a multifactorial disease, in which the contribution of estrogen may be small. However the estrogen-induced changes, together with changes caused by other contributors, can result in osteoarthritis. 展开 ...
In this issue of Osteoarthritis and Cartilage, Dr Pritzker and colleagues1, under the auspices of the Osteoarthritis Research Society International (OARSI), present a recommended methodology for grading and staging histopathologic changes in osteoarthritic cartilage. As the authors note, the commonly used...
Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix. Age-related changes in multiple components of the musculoskeletal system may contribute to the well established link between aging and osteoarthritis (OA)... RF Loeser - 《Osteoarthritis Cartilage》 ...