Chondrocytes created fromadult stem cellsare currently being experimentally used but as they cannot be currently be produced in large amounts, the procedure is expensive. With their huge capacity to proliferate,embryonic stem cells, which can be manipulated to form almost any type of mature cell, ...
Endothelial cells revealed as chondroclasts Osteoclasts are known for their role in bone resorption. A study now shows that a vascular–associated osteoclast subtype at the growth plate also regulates blood vessel growth in bone and is supported by type H endothelial cells. These type H capillaries...
Great histocompatibility of tissue engineering materials are necessary in clinic [35,36]. Cells seeded onto the scaffold must have the ability to attach and proliferate for tissue repair fundamentally [[37], [38], [39]]. The ability of the hydrogels to promote cell adhesion can be observed by...
Cells are either delivered directly to the damaged site or are delivered in a scaffold that acts as a temporary matrix [19,23,26,27]. Studies show better results for ACI compared to MF [23,28]. Doctors and scientists are still looking for an effective method to regenerate cartilage. A ...
a prominence known as theagger nasi air cellsmay be seen. These agger nasi cells are the most anterior ethmoidal air cells, and the mound is formed bymucous membranethat is covering the ethmoidal crest of the maxilla. They lay below thelacrimal sacfrom which they are separated by only a ...
“bulk” tissue analyses4,5,6. This is problematic for a tissue such as synovium, whose cellular constituents are known to be highly heterogeneous. Evidence suggests that many cell populations, including synovial fibroblasts7,8,9,10and immune cells11,12,13,14, play a role in OA pathogenesis,...
Medicinal and surgical approaches are often ineffective, and the supply of autologous chondrocytes for tissue engineering is very limited. Bone marrow stromal cells (BMSCs, also known as bone marrow‐derived mesenchymal stem cells) have been suggested as an adequate cell source for cartilage ...
(white pushpin). Variations in the signal intensity of the central region are observable, such as the globular mineralized features (calcospherites; white arrow in the circle) at the border of the central region and the tessera’s outer edge (white arrow).BCells within lacunar spaces in ...
Identification of genes expressed in human primordial germ cells at the time of entry of the female germ line into meiosis In mammals, primordial germ cells (PGCs) are first observed in the extraembryonic mesoderm from where they migrate through the hindgut and its mesentery to... G Tetsuya,A...
The cells are spheroidal and equally spaced. • Zone III: Deep (radial) zone; occupies up to 45% of the matrix volume and has the highest PG content. The distance between collagen fibrils increases and they are arranged perpendicularly (radially) to the articular surface. Spheroidal cells ...