Carnitine transport and fatty acid oxidation. Biochim. Biophys. Acta (BBA) Mol. Cell Res. 2016, 1863, 2422-2435. [CrossRef]Longo N, Frigeni M, Pasquali M (2016) Carnitine transport and fatty acid oxidation. Biochimica et Biophysica Acta 1863:2422-35....
Long-chain fatty acid is transformed into acyl-CoA after the catalysis of long-chain acyl-CoA synthetase (LACS). The carnitine palmitoyltransferase system then transport acyl-CoA from cytoplasm into mitochondrial matrix for oxidation: CPTI converts acyl-CoAs into acylcarnitines. CACT exchanges ...
Carnitine palmitoyltransferase activity and fatty acid oxidation by livers from fetal and neonatal rats A John,IB Fritz - 《Canadian Journal of Biochemistry》 被引量: 46发表: 1970年 Selective Reversible Inhibition of Liver Carnitine Palmitoyl-Transferase 1 by Teglicar Reduces Gluconeogenesis and ...
Supplemental carnitine and exercise Carnitine is an endogenous compound with well-established roles in intermediary metabolism. An obligate for optimal mitochondrial fatty acid oxidation, it ... EP Brass - 《American Journal of Clinical Nutrition》 被引量: 257发表: 2000年 Supplemental carnitine and exe...
The SCD is an autosomal recessive disorder of fatty acid oxidation characterized by skeletal myopathy, progressive cardiomyopathy, hypoglycemia and hyperammonemia. Most of the OCTN2 mutations identified in humans with SCD result in loss of carnitine transport function. Identifying these mutations will ...
Carnitine, which can be synthesized by the higher animals, is associated with the transfer of fatty substances from the bloodstream to active sites of fatty-acid oxidation within muscle cells. It regulates the rate of oxidation of fatty acids and may afford the means by which a cell can ...
CARNITINE-ACYLCARNITINE TRANSLOCASE-MEDIATED TRANSPORT OF FATTY ACIDS INTO MITOCHONDRIA: ITS INVOLVEMENT IN THE CONTROL OF FATTY ACID OXIDATION IN LIVER1 S Pande,R Parvin 被引量: 0发表: 1980年 Fatty acid import into mitochondria. The mitochondrial carnitine system plays an obligatory role in 尾-...
摘要: Carnitine is well-known for its role in the transport of fatty acids to the mitochondrial matrix, where - oxidation takes place. This work describes novel functions for this compound and novel data on its pharmacokinetics.关键词: Carnitine acetyl-L-carnitine free radical apoptosi acetylation...
Carnitine is a small molecule necessary for energy production, specifically involved in oxidation and transport of fatty acids. An initial randomized, double-blind, placebo-controlled crossover trial of l-carnitine in 24 children with ADHD failed to demonstrate a significant difference compared with pla...
Effect of L-carnitine on the fatty acid oxidation of exogenously administered fat emulsion: G Sandberg, L Bjelton L Ekman, U Enekull L Lindmark (Vitrum Institute for Human Nutrition, Stockholm, Sweden)doi:10.1016/0261-5614(86)90049-X