McMillan JB, Hudson EK, Van Winkle WB: Evidence for malonyl-CoA-sensitive carnitine acyl-CoA transferase activity in sarcoplasmic reticulum of canine heart. J Mol Cell Cardiol 24: 259–268, 1992McMillan JB, Hudson EK, Van Winkle WB: Evidence for malonyl- CoA-sensitive carnitine acyl-CoA ...
It has two isoenzymes, one of which is carnitine acyl-CoA transferase I, positioned on the outer side of the membrane. When fatty acid is catalyzed by acyl-CoA-synthatase to produce acyl-CoA, it is transported by carnitine acyl-CoA transferase I into the membrane. After it has entered ...
2) Acyl-CoA oxidase 肉毒碱脂酰转移酶13) carnitine acyl transferase 肉碱脂酰转移酶 例句>> 4) Carnitine acyl transferase-1 肉碱棕榈酰基转移酶-15) carnitine palmitoyl transterase-1(CPT-1) 肉毒碱棕榈酰转移酶-1 1. The following indexes were examined,such as the contents of TC,TG,LDL...
car·ni·tine palmi·to·yl·trans·fer·ase 1.an enzyme that reversibly forms acylcarnitines and coenzyme A from carnitine and acylcoenzyme A (often, palmitoyl-CoA); important in fatty acid oxidation. Deficiency of isozyme I results in ketogenesis with hypoglycemia; deficiency of isozyme II affe...
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Carnitine is actively transported via OCTN2 into the cytosol to participate in the shuttling of activated long chain fatty acids into the mitochondria where β-oxidation takes place. Carnitine also regulates the Coenzyme A (CoA)/acylCoA ratio within the mitochondria, modulation of which reduces accum...
carnitine octanoyltransferaseacyl-CoA thioesterase 5acyl-CoA thioesterase 12β-oxidationperoxisomesPeroxisomes metabolize a variety of lipids, acting as a chain-shortening system that produces acyl-CoAs of varying chain lengths, including acetyl-CoA and propionyl-CoA. It is, however, still largely ...
The role of carnitine via the action of carnitine acyltransferase in buffering CoA availability in the mitochondrial matrix is well known. There is now sufficient evidence to extend this to a general role. Carnitine can buffer the acylation state of the CoA pool for any type of acyl group that...
Carnitine is actively transported via OCTN2 into the cytosol to participate in the shuttling of activated long chain fatty acids into the mitochondria where β-oxidation takes place. Carnitine also regulates the Coenzyme A (CoA)/acylCoA ratio within the mitochondria, modulation of which reduces accum...
(ACS) catalyzes formation of the corresponding long-chain fatty acyl CoA (e.g., palmitoyl CoA). Subsequently, palmitoyl CoA is converted to palmitoylcarnitine through the action of carnitine palmitoyl transferase I (CPT I). Palmitoylcarnitine then passes into the mitochondrial intermembrane s...