2024年5月7日,刘文教授团队在Journal of Medicinal Chemistry杂志上在线发表题为A CARM1 inhibitor potently suppresses breast cancer both in vitro and in vivo的研究成果。该研究通过大规模筛选获得了高效和特异性靶向CARM1酶活性的新型小分子抑...
CARM1-IN-1电议VIP6年北京普西唐生物科技有限公司2024-06-05询价 CARM1-IN-1￥1900/瓶上海源叶...VIP12年上海源叶生物科技有限公司2024-11-28询价 CARM1 inhibitor 1￥1904/支上海VIP4年凯梅根(上海)生物科技有限公司2025-01-23询价 北京百奥莱博科技有限公司王欣 即时洽谈...
Figure 1. Carm1 is an epigenetic inhibitor in tumor-specific T cells Figure 2. Carm1 inhibition in CD8 T cells enhances their anti-tumor function Figure 3. Inactivation of Carm1 gene in tumor cells elicits tumor immunity Figure 4. Innate immune activation in Carm1 deficient tumor cells Figure...
9.本发明第一个方面为,carm1抑制剂在制备肿瘤铁死亡诱导剂的应用;本发明第二个方面为,carm1抑制剂在制备索拉非尼增敏剂中的应用,其特征在于,所述索拉非尼增敏剂用于治疗和/或抑制索拉非尼治疗耐药的肿瘤;进一步的,根据第一方面和/或第二方面任一所述的应用,所述carm1抑制剂为carm1 inhibitor(217531) [0010]...
CARM1 inhibitor 9英文别名: CARM1 inhibitor 9;1-Piperidineethanamine, 4-[[(3-bromophenyl)methyl]amino]-N-methyl-中文名: 中文别名: CBNumber: CB44844611 分子式: C15H24BrN3 分子量: 326.28 MOL File: 2180931-09-1.mol 化学性质 安全信息 用途 供应商 1 ...
别名:Protein Arginine Methyltransferase 4/CoactivatorAssociated Arginine Methyltransferase 1 Inhibitor 分子式:C26H21Br2NO3 分子量:555.26 纯度:>98% 溶解度:DMSO : ≥ 35 mg/mL (63.03 mM) 储存:Store at -20°C 库存:现货 Background PRMT4/CARM1 Inhibitor selectively blocks the activity of PRMT4/CAR...
CARM1 inhibitor 1 hydrochloride CAS:2070018-31-2 产品属性: 纯度:98%; 包装规格:5 mg; 用途:科学研究、研发; 货号:C106334; 品牌:ChemeGen; 产地:上海; 价格: ￥1904/支、 更新日期:2025/01/23 北京普西唐生物科技有限公司 VIP6年 备 营业执照和法人身份证已备案 即时洽谈 立即询价 联系电话...
32 More recently, compound 43, a potent and selective CARM1 inhibitor, displayed good in vivo efficacy for solid tumors.31 However, some of these CARM1 inhibitors possess excellent inhibitory activity but are not specific for CARM1 due to the high homology of PRMT family proteins or exhibit ...
Total cell lysates were analyzed from NFIB WT/KO HeLa cells, CARM1 WT/KO MEFs and WT MEFs treated with CARM1 inhibitor (CARM1i, TP-064). Actin shown as a loading control. f IP-MS was performed, in triplicate, on cell lysates from WT or Carm1−/− MEFs using the NFIBme2a ...
SGC2085是一种具有高效性和选择性的CARM1抑制剂,IC50值为50nM。注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!CAS号:1821908-48-8纯度:99.10%分子式:C19H24N2O2分子量:312.41结构式:储存条件:-20℃,有效期2年,溶入溶剂后-20℃请尽量在一个月内使用。相关搜索:CARM1抑制剂(SGC2085),1821908-48-8...