In many ways, cardiac muscle is something of a hybrid between skeletal and visceral "smooth" muscle. In its unceasing electrical and mechanical rhythmicity, it is reminiscent of many single-unit visceral muscles, but in its banded appearance, it resembles more the nature of skeletal muscle than ...
Skeletal muscle Long syncytial, multinucleated cells; orderly arrangement of myosin and actin filaments gives striated appearance; each fiber is directly innervated by a motor neuron Rapid, powerful contractions; can shorten to 60%–80% of resting length; contraction is initiated by the central nervou...
Tissue engineered heart muscle implanted on to the epicardium can structurally and functionally remuscularize the failing hearts of rhesus macaques, with no major adverse effects; a clinical trial of this approach is now underway in patients with heart failure. ...
Regeneration of cardiac muscle in adult salamanders and teleost fish has been attributed to dedifferentiation and proliferation of pre-existing cardiomyocytes1,2,3,4,5,6,7,8,9. Cardiomyocytes can re-enter the cell cycle in the adult mammalian heart but this does not lead to functional regeneratio...
1. Cardiac muscle 2. Smooth muscle 3. Skeletal muscle Types of muscle The three types of muscle are skeletal, smooth and cardiac. Skeletal muscle is striated, is attached to the skeleton and responsible for voluntary movement. Smooth muscle ...
Muscle cells: Muscle tissues in the human body are of three types, namely, skeletal muscle, cardiac muscle, and smooth muscle. Cardiac muscle tissue makes up the wall of the heart. The skeletal muscle is attached to the skeletal ...
Both γ2-3B and γ3, in cardiac and skeletal muscle respectively, are present along the Z-disk and in the I band; both staining patterns closely resemble the respective T-tubule/SR structures. The different appearance of γ2-3B and γ3 staining reflects the structural differences of the T...
no single-cell specific marker that delineates fibroblast or myofibroblast cells. To characterize the cells of fibroblast origin, vimentin is commonly used. Cardiac fibroblasts can be identified using discoidin domain receptor 2 (DDR2) while α-smooth muscle actin is used to distinguish myofibroblasts...
The heart is commonly described as being composed of muscle fibers, but the interpretation of fibers is a matter of scale resulting from the average orientation of myocytes within a layer over larger distances. When viewed at cellular resolution, single fibers are not identifiable. The system to ...
The HL-1 cell line, a mouse cardiac muscle cell line, is derived from the AT1 mouse atrial cardiomyocyte tumor lineage24. HL-1 cells were used for ChIP assays and cellular functional assays. Before induction of hypoxia in cells, the medium was replaced with a sugar-free and serum-free ...