Cardiac Amyloidosis: Clinical Features, Pathogenesis, Diagnosis, and Treatmentdoi:10.5146/tjpath.2023.12923CARDIAC amyloidosisIMMUNOGLOBULIN light chainsDIAGNOSISAMYLOIDOSISHEART failureCardiac amyloidosis is a type of amyloidosis that deserves special attention as organ involvement significantly worsens ...
However, endomyocardial biopsy is the definitive diagnostic, recent developments in imaging techniques and extracardiac tissue sampling have minimized the need for invasive endomyocardial biopsy for amyloidosis. Despite advances in treatment, the prognosis for patients with amyloidosis is still poor and ...
Primary amyloidosis with cardiac involvement presenting as congestive heart failure (CHF) usually carries an unfavorable prognosis, with median survival of about 6 months. We are reporting a case of cardiac amyloidosis with an initial presentation of CHF in which the patient survived for more than 9...
Hachulla E, Maulin L, Deveaux M, Facon T, Blétry O, Vanhille P, Wechsler B, Godeau P, Levesque H, Hatron PY, Huglo D, Devulder B, Marchandise X (1996) Prospective and serial study of primary amyloidosis with serum amyloid P component scintigraphy: from diagnosis to prognosis. Am ...
The combination of serum NT-proBNP (N-terminal prohormone of brain natriuretic peptide) and troponin is useful to stratify prognosis and guide treatment strategies in AL amyloidosis.16 Electrocardiography Because the thickening of the ventricular wall in amyloidosis is due to myocardial infiltration ...
6-8 The aims of this study were to assess the ability of CMR with native T1 mapping to measure the cardiac response to treatment and the association between changes in native T1 and prognosis. Methods Study participants comprised individuals with cardiac AL amyloidosis diagnosed at the...
The clarification of mechanisms of cardiac damage is offering new potential therapeutic targets, and several treatment options with a relevant impact on prognosis are now available. 展开 关键词: Cardiac amyloidosis Heart failure NT-proBNP Cardiac imaging Diastolic function Systolic function Cardiac toxicity...
"The heart is the most important abnormality in amyloidosis because if the heart is affected, that is the complete driver of how the patient will do and what their prognosis is," says Dr. Grogan. "That's why cardiac amyloidosis is so important to recognize and treat as early as possible....
New and Evolving Concepts Regarding the Prognosis and Treatment of Cardiac Amyloidosis The clarification of mechanisms of cardiac damage is offering new potential therapeutic targets, and several treatment options with a relevant impact on ... S Perlini,R Mussinelli,F Salinaro - 《Current Heart Failu...
Cardiac amyloidosis or amyloid cardiomyopathy (ACM), commonly resulting from extracellular deposition of amyloid fibrils consisted of misfolded immunoglobulin light chain (AL) or transthyretin (TTR) protein, is an underestimated cause of heart failure and cardiac arrhythmias. Among the three types of card...