or optional conversion of the resulting ester to an amide by conventional means, or optional conversion of the resulting ester or amide to a carboxylic acid or salt thereof by conventional hydrolysis means; (ii) when X is an oxygen or sulphur atom, by reaction of a phenol or thiophenol deri...
Thus, for example, 7-amino-3-vinyl-3-cephem-4-carboxylic acid is reacted with 2-mercapto-1,3-benzothiazolyl-(Z)-2-(2-aminothiazol-4-yl)-2-(methoxycarbonyl)-methoxyimino acetate in tetrahydrofuran and water at 4° C. in the presence of triethylamine. The reaction mass is extracted ...
The report presents the first method for simultaneous determination of plasma 2-(3-hydroxy-5-phosphonooxymethyl-2-methyl-4-pyridyl)-1,3-thiazolidine-4-carboxylic acid (HPPTCA), an adduct of cysteine (Cys) and active form of vitamin B6 pyridoxal 5′-phosp
Design strategy for controlling the reaction selectivity over MnO x catalysts. Schematic illustration of the strategy for achieving the selectivity-tunable aerobic ammoxidation of hydroxyaldehyde by an organic carboxylic acid-modified MnO x catalyst Full size image Carboxylic acid-modified MnO x were prepa...
Thus, the sodium salt of isobutyrodithioic acid 14, after activation with boron trichloride, gives a smooth reaction with ammonia, methylamine, dimethylamine, or pyrrolidine to give the corresponding thioamides (equation 4).21 The approach may be extended to the synthesis of α-phosphono...
-phenylcaproicacid Chapter143=> IUPACNames Remove-efromalkane(oralkene)name,add-oicacid.Thecarbonofthecarboxylgroupis#1.ClOCH3CH2CHCOH PhCHC HCOOH 2-chlorobutanoicacidtrans-3-phenyl-2-propenoicacid(cinnamicacid)=> Chapter144 NamingCyclicAcids Cycloalkanesbondedto-COOHarenamedas...
reaction incorporating ethyl bromodifluoroacetate170, zinc and a series ofaliphatic aldehydes(Equations (81)–(83)). Subsequent enzymatic resolution of racemic ethyl 2,2-difluoro-3-hydroxyoctanoate171via a hydrolysis procedure afforded the corresponding chiral nonracemiccarboxylic acidin good yields and...
acid. Base-catalyzed decarboxylation can also be achieved and, generally, milder conditions are required for the 2-carboxylic acids than for the 3-isomers. The reaction is also promoted by electron-donating substituents and retarded by electron-withdrawing groups. Thus, for example, steam ...
A method for the production of a salt of carboxylic acid by catalytic dehydrogenation effected by reacting the corresponding primary alcohol in aqueous solution with an alkaline hydroxide in the present of a copper catalyst, in which, be... A Villanti,G Conti - EP 被引量: 29发表: 1985年 ...
4. The compound of claim 1, which is selected from 3-methyl-2-(6-phenyl-3,4-dihydro-1H-isoquinoline-2-sulfonylmethyl)butyric acid, 2-(6-cyclohexyl-3 ,4-dihydro-1 H-isoquinoline-2-sulfonylmethyl)-3-methylbutyric acid, 2-(6,7-dimethoxy-3 ,4-dihydro-1 H-isoquinoline-2-sulfonylmethyl)...