(VSS) is 1.24±0.439 L/kg. This is a previously unknown value (due to the lack of an IV formulation) the now permits precise dosing of an IV formulation to attain a targeted plasma CBZ concentrations as might be required when initiating therapy in patients whose oral therapy has been ...
Reference to a study by T. Hayashi and colleagues, published in the January 2005 issue of the "International Journal of Urology"; Anti-epileptic drugs received by the patient; Dosage of carbamazepine administered to the patient; Outcome of switching carbamazepine to phenytoin ...
The type strain CBZ_1T was tested for its ability to degrade carbamazepine and ibuprofen. Initially, the biodegradation tests were conducted in triplicates in 50 ml of Bushnell-Haas mineral medium (CaCl2·2H2O 0.002 g, MgSO4·7H2O 0.02 g, NH4NO3 1 g, KH2PO4 1 g, K2HPO4 1 g, FeCl3...
Carbamazepine-10,11-epoxide is a potent anticonvulsant in animal models. During treatment with carbamazepine the plasma concentrations of this metabolite are usually 10 to 50% of those of the parent drug. It has not been possible to establish the relative contribution of the two compounds to the ...
Carbamazepine (CBZ) is one of the most common emerging contaminants released to the aquatic environment through domestic and pharmaceutical wastewater. Due to its high persistence through conventional degradation treatments, CBZ is considered a typical indicator for anthropogenic activities. This study tested...
to prevent the release of residues in water bodies; (iii) introduce the use of orientated approaches, such as disease prevention, improved diagnostics, and restrictions on pharmaceuticals with high environmental risk, to reduce inappropriate and excessive consumption; and (iv) implement end-of-pipe ...
Introduction Pharmaceuticals and personal care products (PPCPs) as emerging organic pollutants have received more and more attention during the past decades, due to their frequent detection in the soil environment and their long-term potential risks to soil organisms and aquatic systems [1,2]. PPC...
20 September 2017 Abstract: In this study, the aim was to evaluate the adsorption capacity of a volcanic rock commonly used in Mexico as filter medium in constructed wetlands (locally named tezontle) for carbamazepine (CBZ) adsorption, as well as to analyze the change in its capacity with bio...
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