Herein we report a significant interaction between carbamazepine (CZP) and apixaban, causing subtherapeutic concentration of the drug in a patient with atrial fibrillation who had a transient ischemic attack (TIA) episode. Another anti-Xa DOAC, edoxaban, administered to the patient after TIA ...
Apixaban Apremilast Aprepitant Aripiprazole Artesunate Atogepant Avacopan Avapritinib Axitinib Bedaquiline Belumosudil Bendamustine Benzhydrocodone Benzphetamine Berotralstat Betrixaban Bictegravir Bortezomib Bosutinib Brexpiprazole Brigatinib Buprenorphine Bupropion Butorphanol Cabozantinib Calcifediol Cannabidiol Capma...
HIV medications such as indinavir and ritonavir estrogen or progestin-containing oral contraceptives and hormonal treatments medications that cause drowsiness, such as benzodiazepines, sedating antihistamines, and sleeping pills medications that reduce the risk of blood clotting, such as apixaban or dabigatra...
11-epoxide, which is further metabolized to the trans-diol by epoxide hydrolase. Therefore, the potential exists for interaction between carbamazepine and any agent that inhibits CYP3A4 and/or epoxide hydrolase. Agents that are CYP3A4 inhibitors that have been found, or are expected, ...
Apixaban Apremilast Aprepitant Aripiprazole Axitinib Bedaquiline Blinatumomab Bosutinib Brexpiprazole Bupropion Cabozantinib Cariprazine Ceritinib Chlorpromazine Clarithromycin Clonazepam Clozapine Cobimetinib Conivaptan Crizotinib Cyclophosphamide Cyclosporine Dabigatran Etexilate ...
Interaction Checker Enter a drug name to check for any interactions. and carbamazepine All Interactions Sort By: Contraindicated (46) apixaban artemether/lumefantrine atazanavir cabotegravir cariprazine cobimetinib darunavir dienogest/estradiol valerate doravirine efavirenz elbasvir/grazoprevir elvitegravir/cob...
Apixaban Concentration with and without Coadministration of Carbamazepine: A Case with No Apparent InteractionThe direct-acting oral anticoagulants (DOACs) have many advantages over warfarin. In particular, apixaban has rapid onset (1-3 h) and offset (half-life 8-15 h) of action, with ...
Carbamazepine is metabolized by CYP3A4. Therefore, the potential exists for interaction between carbamazepine and any agent that induces CYP3A4. Agents that are CYP inducers that have been found, or are expected, to decrease plasma levels of Carbatrol include, for example, the following: ...
Anticoagulants (e.g., apixaban, dabigatran, edoxaban, rivaroxaban, warfarin) Warfarin: Carbamazepine may induce metabolism of and decrease plasma concentrations of warfarin Apixaban, dabigatran, edoxaban, rivaroxaban: Possible decreased plasma concentrations and reduced efficacy of the anticoagulant Warfarin:...