参考资料 [1]Zhang L,et al.CAR-NK cells for acute myeloid leukemia immunotherapy: past, present and future. Am J Cancer Res. 2023 Nov 15;13(11):5559-5576.https://pmc.ncbi.nlm.nih.gov/articles/PMC10695781/ [2]Liu E,et al.Use of CAR-transduced natural killer cells in CD19-positive ...
CAR-NK，全称为“嵌合抗原受体自然杀伤细胞”（Chimeric Antigen Receptor-Natural Killer Cells），听名字可能有点拗口，翻译过来就是“带着GPS导航的免疫杀手”。这是一种经过基因改造的NK细胞，它们被赋予了精准找到并摧毁癌细胞的能力，简直像古代游侠“路见不平拔刀相助”一般果断。相比于传统的CAR-T疗法，这些“...
[1]Marin D,et al.Safety,efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19+B cell tumors: a phase 1/2 trial. Nat Med. 2024 Mar;30(3):772-784.https://www.nature.com/articles/s41591-023-02785-8 [2]Sauter C S,et al.A Phase 1 Study of NKX1...
[1]Marin D,et al.Safety,efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19+ B cell tumors:a phase 1/2 trial[J].Nature Medicine,2024: 1-13.https://www.nature.com/articles/s41591-023-02785-8 [2]Wang J,et al.Umbilical cord blood derived cellular ...
P. (2021). CAR-NK cells in the treatment of solid tumors. International journal of molecular sciences, 22(11), 5899.[2] Zhang, L., Meng, Y., Feng, X., & Han, Z. (2022). CAR-NK cells for cancer immunotherapy: From bench to bedside. Biomarker Research, 10(1), 1-19.
CAR-NK cells: A promising cellular immunotherapy for cancer. EBioMedicine. 2020;59:102975. 赛业生物细胞治疗一站式解决方案 助力肿瘤免疫细胞治疗临床前研究 在CAR-T其他细胞治疗的临床前研究中,细胞模型、动物模型的选择都至关重要,明确研究的目的,建立有效的实验模型和方案,会使研究事半功倍。赛业生物提供细胞...
[1]Marin D,,et al.Safety,efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19+B cell tumors: a phase 1/2 trial. Nat Med. 2024 Mar;30(3):772-784. doi: 10.1038/s41591-023-02785-8. Epub 2024 Jan 18. nature.com/articles/s41 [2]Wang W,et al....
[2]Li J,et al.CAR-NK cells in combination therapy against cancer: A potential paradigm[J]. Heliyon, 2024. https://www.cell.com/heliyon/fulltext/S2405-8440(24)03227-4 [3]Li C,et al.Robo1-specific chimeric anti...
[2]Zhang, L,et al.CAR-NK cells for cancer immunotherapy: from bench to bedside.Biomark Res10, 12 (2022).https://biomarkerres.biomedcentral.com/articles/10.1186/s40364-022-00364-6 [3]Li C,et al.Robo1-specific chimeric antigen receptor natural killer cell therapy for pancreatic ductal ...
参考资料 [1]Marin D,et al.Safety,efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19+ B cell tumors:a phase 1/2 trial[J].Nature Medicine,2024: 1-13. https://www.nature.com/ar...