Protocol for the examination of specimens from patients with invasive carcinoma of the breast.(CAP Laboratory Improvement Programs)(Report)Lester, Susan CBose, ShikhaChen, YunnYiConnolly, James Lde Baca, Monica EFitzgibbons, Patrick LHayes, Daniel F...
However, this biomarker is only expressed in 20% of a11 breast tumors [8]; therefore additional breast cancer markers are rigorously being explored [9]. Mucins are promising candidates [10] in particular, CA 15-3, a MUCI tumor Marker; this cancer antigen is overexpressed in >90% of breast...
J. Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells. J. Cell Biol. 164, 603–612 (2004). 32. Inman, J. L. & Bissell, M. J. Apical polarity in three-dimensional culture systems: where to now? J. Biol. 9...
Dr Buxton reported receiving grants from the Breast Cancer Research Foundation during the conduct of the study and grants from Bayer, Amgen, Eli Lilly and Company, Janssen, Kazia Therapeutics, DelMar Pharma, Eisai, the National Brain Tumor Society, the National Foundation for Cancer Research, and ...
[26]. Normal tissue contamination or unknown ploidies of tumor cells is another challenges for array-based platform. In HER2 testing for breast or gastric cancer, in situ hybridization method is the gold standard to assess patient’s further treatment [27]. In this study, the prognostic ...
Neuroblastoma is the most common extra-cranial pediatric solid tumor, responsible for 13–15% of pediatric cancer death. Its intrinsic heterogeneity makes it difficult to target for successful therapy. The adaptor protein p140Cap/SRCIN1 negatively regula
Capzimin exhibits promising activity in leukemia cells including the SR and K562 cell lines (GI50 values of 0.67 μM and 1 μM respectively), as well as several solid tumor cell lines including NCI-H460 (non-small cell lung cancer; GI50= 0.7 μM) and MCF7 (breast cancer; GI50=1.0 μ...
The addition of methyl groups to the 5' carbon position of cytosine bases is a major mechanism of epigenetic regulation which participates in reorganizing chromatin structure and silencing gene expression [2], Epigenetic alterations, such as tumor suppressor gene hypermethylation and oncogene ...
Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression Cancer Res, 71 (15) (2011), pp. 5090-5100 View in ScopusGoogle Scholar [66] J. Kim, H.Y. Gee, M.G. Lee Unconventional protein secretion - new insights into the pathoge...
J. Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells. J. Cell Biol. 164, 603–612 (2004). Article CAS PubMed PubMed Central Google Scholar Inman, J. L. & Bissell, M. J. Apical polarity in three-dimensional ...