Does THC in cannabis help treat HIV symptoms? Where are CB2 receptors located in the human body? What are cannabinoids? What is THCV good for? What is Cannabidiol (CBD)? What is THCA? Does Marinol (synthetic THC) work the same as THC found in cannabis? What are the different types of...
A surrogate mouse model to induce polyclonal T cell responses against HIV(gp120) was established. THC, a marijuana-derived cannabinoid, suppressed or enhanced mouse CD8(+) T cell proliferation and the gp120-specific CTL response depending on the magnitude of the IFN-纬 response. To determine ...
Influence of tetrahydrocannabinols (delta8-THC and delta9-THC) on body weight, food, and water intake in rats. Pharmacol Biochem Behav 1973; 1: 395–399. Article CAS PubMed Google Scholar Fernandes M, Schabarek A, Coper H, Hill R . Modification of delta9-THC-actions by cannabinol and...
including cancer and neuropathic pain1. The synthetic version of its psychoactive constituent, Δ9-tetrahydrocannabinol (THC, Fig.1), is in FDA approved drugs Marinol® or Syndros® (dronabinol). The extracted version of THC is one of the active constituents of oromucosal spray...
As used herein, a “cannabinoid” is a chemical compound (such as cannabinol, THC or cannabidiol) that is found in the plant speciesCannabis sativa(marijuana), and metabolites and synthetic analogues thereof that may or may not have psychoactive properties. Cannabinoids therefore include (without li...
In addition to preventing the release of neurotoxic cytokines and reactive oxygen species, CB2R activation may actually reduceHIV infectionin the CNS. Δ9-tetrahydrocannabinol (Δ9-THC) acts through CB2Rs to reduce expression of the CD4, CXCR4, andCCR5 receptorsthat are required for HIV infection...
INTRODUCTION Synthetic cannabinoid designer drugs have emerged as drugs of abuse during the last decade and produce psychoactive effects resembling those of delta-9-tetrahydrocannabinol (Δ9- THC), the main active constituent of cannabis, through binding to the same cannabinoid receptors CB1 and CB2 (...
Endocannabinoid signaling at the periphery: 50 years after THC. Trends Pharmacol. Sci. 2015, 36, 277–296. [CrossRef] 9. Mackie, K. Distribution of cannabinoid receptors in the central and peripheral nervous system. In Handbook of Experimen- tal Pharmacology; Cannabinoids; Pertwee, R.G., Ed...
Delta-9-tetrahydrocannabinol or Delta-9 THC, the principle active component of Cannabis sativa (marijuana), is a member of a large family of lipophilic compounds (i.e., cannabinoids) that mediate physiological and psychotropic effects including regulation of appetite, immunosuppression, analgesia, ...
Delta-9-tetrahydrocannabinol or Delta-9 THC, the principle active component of Cannabis sativa (marijuana), is a member of a large family of lipophilic compounds (i.e., cannabinoids) that mediate physiological and psychotropic effects including regulation of appetite, immunosuppression, analgesia, ...