T-cell lymphomaMalignant lymphomas are one of the most common malignancies occurring in dogs; among them T-cell tumours are less commonly recognized. Recently, many authors have recommended cytology as a sufficient diagnostic method for canine lymphomas, especially if supported by immunocytochemistry or...
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In Lymphoma, the regulation of production is lost and these cells proliferate in large number, or they lose their programed life cycle and continue to live on, overwhelming the other blood cells. High white blood cell count and swollen lymph glands are the characteristic signs of this disease,...
Musser ML, Clifford CA, Bergman PJ et al (2022) Randomised trial evaluating chemotherapy alone or chemotherapy and a novel monoclonal antibody for canine T-cell lymphoma: a multicentre US study. Vet Rec Open 9:e49. https://doi.org/10.1002/vro2.49 Article PubMed PubMed Central Google Scholar...
Canine small clear cell/T-zone lymphoma: clinical presentation and outcome in a retrospective case series. Vet Comp Oncol. Doi: 10.1111/vco.12155 [epub ahead of print].Martini V, Marconato L, Poggi A, et al. Canine small clear cell/T-zone lymphoma: clinical presentation and outcome in a ...
These genes include hyaluronidase-coding genes HYAL4 and SPAM1, related to cell proliferation and invasion [47, 48], SEL1L, linked to reduced tumour aggressiveness [49], TRAF3, a tumour suppressor found mutated in canine B cell lymphoma [50, 51], c-kit, involved in MCT pathogenesis [8,...
Canine T-cell lymphomas: a morphological, immunological, and clinical study of 46 new cases. The aim of this study is to report 46 new cases of canine T-cell lymphomas among a series of 140 lymphomas studied by immunophenotyping (incidence 32.8%). ... C Fournel-Fleury,F Ponce,P Felman,...
fluorescence signals were detected by a LI-COR Imager with Image Studio Lite software (LI-COR Biosciences GmbH). The Western blot analysis was repeated three times with subsequent passages. Protein lysates of the lymphoma cell lines GL-1 (canine), NALM-6 and SEM (both human) served as positi...
In diffuse large B-cell lymphoma (DLBCL), the most common sub- type of human B-cell lymphomas, the numbers of T-cells are positively correlated to the prognosis in patients [15]. This highlights the significance of "functional" T-cells in B-cell lymphoma patients. Tumor-induced T-cell ...
The aim of this study was to investigate the mRNA and protein expression of VEGF and the most relevant MMPs in canine lymphoma. Lymph node aspirates from 26 B-cell and 21 T-cell lymphomas were collected. The protein expression levels of MMP-9, MMP-2 and VEGF-A were evaluated by ...