For the clinical staging of breast cancer, your oncologist will palpate (physically touch) areas of skin nearest the tumor to feel for lumps. The clinical staging is ultimately based on the number, size, texture, and location of swollen lymph nodes.1 Alternatively, your lymph nodes may be eva...
Tumor content chart-assisted digital PCR analysis is also applicable to multiple sites in surgically resected tissues. These results indicate that this analysis is a useful alternative to HER2 immunohistochemistry in gastric cancers that can serve as a basis for the automated evaluation ofHER2status. ...
Progress in understanding the complexity of a devastating disease such as cancer has underscored the need for developing comprehensive panels of molecular markers for early disease detection and precision medicine applications. The present study was conducted to assess whether a cohesive biological context ...
Fig. 5: TEDs. a, Workflow representing the number of treatment groups in each step of the analysis. For the external layers of the pie chart, the number of treatments with identified TEDs is coloured by cancer type. For the internal layers of the pie chart, the category of the correspondi...
TCGA data is mRNA data-based and may not always reflect their protein expression. Second, it is also possible that while high expression of XIAP is associated with better survival in ccRCC (Fig.4A), XIAP can still be a target for tumor elimination. This notion has been demonstrated in the...
Cancer prognosis: Considering tumor and its microenvironment as a whole EBioMedicine, Volume 43, May 2019, Pages 28-29 Dan Qi, Erxi WuView PDFAbstract Background Tumour microenvironment (TME) is critical for the regulation of cancer development as well as therapy. The objective of the current ...
Table S1. Proportion test of significant bacteria between normal breast and breast tumor, related to Figure 1 Table S2. Proportion test of significant bacteria between tumor tissue and tumor cell, related to Figure 2 Table S3. Four bacterial clusters in normal breast, breast tumor, met adjacent...
Conclusion: Our findings suggests that CK5/6 and/or EGFR expressing tumor types have a persistently poorer prognosis over the longer term, an observation that may have important therapeutic implications as drugs that target the EGFR are currently being evaluated in breast cancer. Page 1 of 11 (...
Endometrial cancer (EC) is the most common malignancy of the female reproductive system. Cancer antigen 125 (CA125) is a serum tumor marker widely reported in EC patients, particularly those with poor prognostic factors such as grade 3 tumors, deep myome
aUMAP visualization of macrophage subsets in the atlas.bHierarchical clustering analysis indicating similarity of clusters in terms of average expression.cDotplot showing the percentage of cells expressing (size) and mean expression (colour) of top 2 most significantly upregulated markers per cluster.d...