There are instances in which chemo might take a step back to other treatments that might have milder side effects. With new advances and treatments in personalized care, experts can now personalize the cancer treatment depending on the individual needs of their patient and to what type of cancer...
Besides intratumoral injection, several nanotherapeutic systems can also be surgically implanted at or near tumor sites for the direct elimination of solid tumors, or at tumor resection sites for the prevention of cancer recurrence.147,149A DOX-loaded nanofibrous membrane that was implanted on the top...
Fourthly, the treatment landscape has expanded from monotherapy to combination therapies, encompassing a variety of immunomodulators, anti-angiogenic drugs, chemotherapies, and targeted therapies. Lastly, a diverse array of treatments, including previously ‘undruggable’ targets, peptide drugs, monoclonal a...
Besides, cyanine conjugates that serve as nanocarriers for drug delivery are introduced as well. In an additional section, we analyze the potential of these conjugates for clinical translation. Overall, this review is aimed to stimulate research interest in exploring unattempted therapeutic agents and ...
Guo et al. used an insightful nanoplatform for drug delivery to accomplish a PTT-chemo. The paramagnetic iron oxide nanoparticles were created and enclosed in Mcl-1-siRNA and DOX. The plasma membrane of the MCF-7 tumor was then applied to the encapsulated nanoparticles, enabling the primed ...
Besides, except for the high-dose group, the body weight of mice was maintained stable, and the state of mice was normal. Conclusions In this study, we proved CD276 CAR-T exhibited powerful activity against pancreatic cancer cells in vitro and in vivo. More importantly, we demonstrated the ...
Many cancers adapt to chemo- and radiation therapy: according to some researchers, the clonal selection leads to the resistance of recurrent tumors [36]. If “cancer-embryos” are nurtured in various conditions before they proceed to active life-cycling, they might give birth to distinct “...
[194,195]. Besides, the DNA nanorobot can perform Boolean logic operations on the cancer cell membrane and has a great theranostic potential to be used in clinical treatment of cancers. Dolev et al. [196] designed a nanorobot that could detect circulating cancer cells in the blood and expose...
Introduction Cancer is a significant public health issue with a rapidly growing incidence and mortality worldwide,1leading to about 10 million deaths annually.2Chemotherapy is presently one of the most common anti-cancer treatments due to its high efficiency currently.3,4However, its lack of selecti...
(3) Combining autophagy inducers with cancer treatments such as PTT and PDT promotes autophagy activation and enhances tumor therapy efficiency. Zhou et al.191 used polydopamine nanoparticles (PDA), autophagy-inducing peptide Beclin 1, PEG and cyclic Arg-Gly-Asp (RGD) peptides to synthesize PPBR...