Fourthly, the treatment landscape has expanded from monotherapy to combination therapies, encompassing a variety of immunomodulators, anti-angiogenic drugs, chemotherapies, and targeted therapies. Lastly, a diverse array of treatments, including previously ‘undruggable’ targets, peptide drugs, monoclonal a...
1leading to about 10 million deaths annually.2Chemotherapy is presently one of the most common anti-cancer treatments due to its high efficiency currently.3,4However, its lack of selectivity for tumor cells and challenges in efficient drug delivery to the tumor site have led to practical...
Troy Clark was diagnosed with Stage 3 Prostate Cancer back in 2018. After watching his father go through chemo and radiation therapy on three different occasions, Troy wanted to explore other options. Through a referral of a friend, he found Immunity Therapy Center. “Everyone at ITC treats me...
Theoretically, drug repurposing can help to solve the current problem of no access to the newest drugs for many cancer patients, and also help to reduce financial toxicity to patients who can afford the newest treatments. The fact that highly selective drugs (targeted therapy) lead to Funding ...
[194,195]. Besides, the DNA nanorobot can perform Boolean logic operations on the cancer cell membrane and has a great theranostic potential to be used in clinical treatment of cancers. Dolev et al. [196] designed a nanorobot that could detect circulating cancer cells in the blood and expose...
There are instances in which chemo might take a step back to other treatments that might have milder side effects. With new advances and treatments in personalized care, experts can now personalize the cancer treatment depending on the individual needs of their patient and to what type of cancer...
37 Targeted nano-therapy has demonstrated superior efficacy and reduced toxicity compared to traditional anticancer treatments, due to its improved permeability, retention, and minimal side effects. It prolongs the duration for which nano-sized medications remain in the bloodstream and changes how they ...
Besides, except for the high-dose group, the body weight of mice was maintained stable, and the state of mice was normal. Conclusions In this study, we proved CD276 CAR-T exhibited powerful activity against pancreatic cancer cells in vitro and in vivo. More importantly, we demonstrated the ...
Many cancers adapt to chemo- and radiation therapy: according to some researchers, the clonal selection leads to the resistance of recurrent tumors [36]. If “cancer-embryos” are nurtured in various conditions before they proceed to active life-cycling, they might give birth to distinct “...
The vast complexity of cell death pathways, involving numerous genes and mechanisms, necessitates the application of advanced technologies to effectively counteract death resistance in cancer cells. The ability of cancer cells to evade chemo- and radio-therapy by circumventing cell death pathways contrib...