Treatment of testis cancer is one of the shining success stories in oncology. With 7600 cases per year in the USA, it accounts for 1% of all cancers. However, in the young adult man, it accounts for almost 25% of all cancers. The incidence of testis cancer has increased over the past...
Treatment of Extensive-Stage Small-Cell Lung Cancer (Small-Cell Lung Cancer That Remains Incurable With Current Treatment Options) Combination chemotherapy treats people with extensive-stage small-cell lung cancer. Currently, the combination of cisplatin or carboplatin and etoposide (PE) is the most wi...
In summary, in first-line treatment for HER2-negative advanced GC, the addition of anti-PD-1 therapy could improve clinical outcomes in patients with high PD-L1 expression, according to the results from CheckMate-649, ORIENT-16, and RATIONALE-305. For patients with low PD-L1 expression or u...
the mechanisms of action for this remain unclear. In this Perspective, Letai and de The assess the existing mechanisms proposed for the success of chemotherapy, identify gaps in our understanding and suggest principles for improving the utility of conventional chemotherapy to enhance treatment efficacy...
Not too long ago, I read two news reports about cancer treatment in China that make me feel real sad. There is a movie, Dying to Survive, which has become a billion-yuan-success after being released in July this year. It is based on a real-life story of Lu Yong, a Chinese textile...
Traditional therapeutic approaches such as chemotherapy and radiation therapy have burdened cancer patients with onerous physical and psychological challenges. Encouragingly, the landscape of tumor treatment has undergone a comprehensive and remarkable t
With MAF under 0.1%, these approaches can detect 59% of stage I or II lung cancer patients. The complete analysis of the tumor is obtained from the NGS, which makes it easy to tailor the treatment options [32]. In thyroid cancer, NGS provides for a high-throughput sequencing study of ...
Skin cancer is a global threat to the healthcare system and is estimated to incline tremendously in the next 20 years, if not diagnosed at an early stage. Even though it is curable at an early stage, novel drug identification, clinical success, and drug resistance is another major challenge...
Preservation of fertility in some cases is possible and should be discussed during treatment planning, with reproductive-aged women with early-stage gynecologic cancer and with those who desire to preserve fertility. 6.1. Cervical Cancer The standard surgical treatment for cervical cancer is a ...
(3) effective treatment after early detection10,45. The overall impact in clinical practice depends on the success rates in each of these stages. This work addresses only the first stage. With a reasonably accurate method for predicting cancer risk, one can direct appropriate high-risk patients ...