The cancer treatment timeline documents the evolution of therapies over the past 170 years, highlighting the transformative treatments that have emerged to enhance clinical outcomes and improve patients’ quality of life. Starting from the early use of general anesthesia in surgical resections in the m...
1800P Concordance between treatment-naive tissue and circulating tumour DNA (ctDNA) in late stage non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC)doi:10.1016/j.annonc.2020.08.1561C. WoestmannJ. JiangJ.F. PalmaC. Ju...
We have implemented CAS at Yamagata City Hospital Saiseikan (YCHS) and report the results of a retrospective analysis of the outcomes: 5-year overall survival (OS), bPFS, and toxicity of CDFRT with ultrasound image-guided radiotherapy (TPUS-IGRT) for LPCa. CDFRT has many more long-term re...
Current cancer precision medicine strategies match therapies to static consensus molecular properties of an individual’s cancer, thus determining the next therapeutic maneuver. These strategies typically maintain a constant treatment while the cancer is
Immune checkpoint blockade (ICB) therapy is a powerful option for cancer treatment. Despite demonstrable progress, most patients fail to respond or achieve durable responses due to primary or acquired ICB resistance. Recently, tumor epithelial-to-mesenchymal plasticity (EMP) was identified as a critica...
patients with stage III tumors undergoing surgery have a dismal 5-year survival rate between 18 and 50% depending on the dataset. These figures indicate the need for more effective molecularly driven treatment strategies. This review discusses the molecular profile of gastric tumors, the success, an...
Sadly, the whole orthiodox treatment programme for cancer in the UK, ignores all the research and clinical trials in this area, resulting in a greatly worsened state of healthy gut bacteria, underproduction of essential vitamins, and increasing levels of toxins (like nitrosamines, heavy metals an...
This cohort study assesses the antitumor activity of pembrolizumab therapy vs chemotherapy for the treatment of microsatellite instability–high advanced
Nanocarriers have been widely studied and applied in the field of cancer treatment. However, conventional nanocarriers still suffer from complicated preparation processes, low drug loading, and potential toxicity of carriers themselves. To tackle the hindrance, carrier-free nanodrugs with biological activity...
Another widely used anthracycline in the treatment in a broad spectrum of cancers like breast, esophageal carcinomas, endometrial carcinomas, bile duct, pancreatic, gastric, liver, Hodgins and non-Hodgins lymphoma, osteosarcoma, Kaposi’s sarcoma, and soft tissue sarcomas is Doxorubicin [183,184] ...