1800P Concordance between treatment-naive tissue and circulating tumour DNA (ctDNA) in late stage non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC)doi:10.1016/j.annonc.2020.08.1561C. WoestmannJ. JiangJ.F. PalmaC. Ju...
Chinese medicine therapies in cancer treatment are very common in the East. Although it is usually classified as a form of complementary and alternative therapy in the West, Chinese medicine is an independent medical profession in Hong Kong and mainland China. It has a different perspective in und...
Immune checkpoint blockade (ICB) therapy is a powerful option for cancer treatment. Despite demonstrable progress, most patients fail to respond or achieve durable responses due to primary or acquired ICB resistance. Recently, tumor epithelial-to-mesenchymal plasticity (EMP) was identified as a critica...
Forty-six patients were receiving treatment in these early quarters when the hospital moved to its current site in March 1954 (Figs. 4A and B). Additional resources to expand the MD Anderson infrastructure (Fig. 5) and research capacities came from several venues: (1) generous donations from ...
comprehensive reference for understanding the role of exosomes in the metastasis, deterioration, and treatment resistance of tumors. However, the most pivotal questions that remain unresolved are how and to what extent the CDEs work in the process of cancer metastasis between the receptors and ...
Talcum powder is the most widely used consumer talc product. Asbestos in talc could increase the risk of mesothelioma.
cancer immunotherapy; antitumor response; cytokines; immune checkpoints1. Introduction The therapeutic options for cancer treatment have been constantly evolving, resulting in the prolongation of life expectancy among many cancer patients [1]. Nonetheless, cancer is still among the leading causes of ...
have shown significant antitumor activity in many cancer types and have been approved by the FDA as a recommended therapy for cancer treatment [2]. However, immunotherapy has been reported with a low response rate of clinical outcomes, and the overall survival (OS) benefit is limited in a narr...
Preclinical activity has been reported in multiple tumour types, including breast cancer, sarcoma, melanoma and mantle cell lymphoma. The PALOMA-1 Phase II clinical trial randomized 165 women with advanced oestrogen receptor (ER)-positive breast cancer into two treatment groups: the aromatase inhibitor...
Despite these shifts, lung cancer remains the most predominant. Addressing increasing cancer rates requires prioritizing primary interventions to reduce risk exposure, strengthening secondary prevention with a focus on early screening and treatment for the older population, and advancing basic research for ...