the early 1900s were a time ready for exploration into the treatment of metastasis of breast cancer to the central nervous system (cns). in fact, the state of surgical treatment of breast cancer itself was undergoing a significant transition. the first half of the 1800s had been characterized...
Definition Esophageal carcinoma is an extremely deadly disease, and in spite of major advances in cancer treatment, prognosis is poor. The use of radiation therapy in the treatment of esophageal carcinoma was first described in France in the early 1900s; radium was used as a local treatment and...
【改编】Australian scientists say an organic compound used by Indian women to paint dots or bindi on their foreheads could hold the key to a breakthrough in cancer treatment. Rose Bengal (玫瑰红)was first used in the early 1900s as a dye for food textiles and cosmetics. But now it is ...
along with their regulatory approvals. In recent times, there has been hope in the effectiveness of cancer vaccines for therapy as they have been able to stimulate de novo T-cell reactions against
Pathologists first spotted nerve cells lurking in tumors in the early 1900s. But their observations did not capture the attention of cancer biologists for another 100 years or so, Drapkin says. The cancer biologists tended to regard the cells as clinical curiosities, mere bystanders rather than ...
However, these microbes may influence responses to other forms of therapy as well and may also affect treatment-associated toxicity. Based on these influences, there is growing interest in targeting these microbes in the treatment of cancer and other diseases. Yet complexities exist, and a deeper ...
the potential for viruses to induce an antitumor immune response has been known for some time. The earliest clinical references to oncolytic viruses were case reports in the early 1900s, primarily describing the remission of malignancies, usually leukemias or lymphomas, after viral infections or live...
Immune checkpoint blockade (ICB) therapy is a powerful option for cancer treatment. Despite demonstrable progress, most patients fail to respond or achieve durable responses due to primary or acquired ICB resistance. Recently, tumor epithelial-to-mesenchymal plasticity (EMP) was identified as a critica...
century, several organizations have promoted using microorganisms to cure cancer [74]. William Coley pioneered in the early 1900s when it came to using microorganisms to treat cancer [12]. Additionally, it has been shown that some bacteria and viruses have evolved defense systems that obstruct ...
The idea of molecular targeted therapy has a relatively long history. The concept of a chemical that specifically targets a microorganism was first proposed in the early 1900s and expanded to cancer treatment in 1988,22and this concept was renewed and has flourished in the past 20 years.23 ...