Targeted therapy(靶向治疗)uses drugs to stopcancer from growing and spreading. It's a newfor all patients with cancer. At the same time,effective way that is better than other treatmentsdifferent cancers may have the same target.chemotherapy according to the text?With the development of targeted...
根据原文第二段:Standard che motherapy works by hilling cancer cells and so me normal cells .(标准的化学疗法是通过杀死癌细胞和一些正常细胞来工作的。)T argeted tre atment focuses on particular targets inside or on cancer cells .normal cells can survive..(靶向治疗的重点是癌细胞内的特定靶点或...
Targeted therapy drugs work in a few different ways. They may turn off the process in cancer cells that causes them to grow and spread, making cancer cells die on their own or kill cancer cells directly. People with the same type of cancer may have different targets in their cancer cells...
understanding of it have been made since the middle of the 20th century. Those advances led to major improvements in cancer treatment, mainly through the development of methods for timely and accuratediagnosis, selectivesurgery,radiation therapy, chemotherapeuticdrugs, and targeted therapies (agents desig...
In the I-SPY2.2 trial, patients with high-risk stage 2/3 breast cancer received neoadjuvant datopotamab–deruxtecan, followed by sequential chemotherapy with or without targeted therapy, with the option of early surgical resection after each block of therapy. In a subgroup of patients, the seq...
In this Perspective, Wahida et al. consider six riddles in precision oncology that must be solved to achieve better clinical responses to molecular targeted therapies. Adam Wahida Lars Buschhorn Razelle Kurzrock Perspective24 Nov 2022 Targeting the gut microbiota for cancer therapy ...
MEK inhibition overcomes resistance to EphA2-targeted therapy in uterine cancer. Gynecol Oncol. 2021;163(1):181–90. Article CAS PubMed PubMed Central Google Scholar Wang C, Yan FH, Zhang JJ, Huang H, Cui QS, Dong W, et al. OV6(+) cancer stem cells drive esophageal squamous cell ...
proliferation, invasion, metastasis, autophagy, EMT, chemoresistance and radioresistance. Furthermore, preclinical animal studies and clinical studies have illustrated the efficacy of AKIs and AKIs in combination with other standard chemotherapeutic drugs, such as paclitaxel, cisplatin and other targeted ...
M. Protein degraders enter the clinic—a new approach to cancer therapy. Nat. Rev. Clin. Oncol. 20, 265–278 (2023). Article CAS PubMed Google Scholar Wurz, R. P. et al. Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation. Nat. Commun. ...
targeted therapeutics are increasing. Patient-friendly and effective drugs, such as Gleevec, with specific antitumor activity, have changed the paradigm of cancer treatment. The success of Gleevec in the treatment of chronic myeloid leukemia (CML) indicates the importance of discriminating against the ...