Temporal changes in dietary fats: role of n-6 polyunsaturated fatty acids in excessive adipose tissue development and relationship to obesity. The importance of a high fat intake in the increasing prevalence of childhood and adult obesity remains controversial. Moreover, qualitative changes (i.e. ....
The strongest evidence that monunsaturated fat may influence breast cancer risk comes from studies of southern European populations, in whom intake of oleic acid sources, particularly olive oil, appears protective. No previous study has examined the relation of adipose tissue fatty acid content to bre...
Single body mass index (BMI) measurements have been associated with increased risk of 13 cancers. Whether life course adiposity-related exposures are more relevant cancer risk factors than baseline BMI (ie, at start of follow-up for disease outcome) rema
Fig. 1: Flow diagram of participants from matched pancreatic cancer case-control population. *Age-, sex-, and race-standardized reference curves for skeletal muscle and adipose tissue areas were previously developed for white non-Hispanic females and males (18–90 years), black females (18–75 ...
Sex, fat and breast cancer 来自 国家科技图书文献中心 喜欢 0 阅读量: 228 作者:Simpson,Evan R 摘要: Simpson ER.关键词:Adipose Tissue Humans Breast Neoplasms Obesity Aromatase Female DOI: 10.1080/09513590802296153 被引量: 4 年份: 2009 收藏 引用 批量引用 报错 分享 ...
Exercise also pares off hormonally active fat tissue. Fat manufactures substance called Aromatase that converts hormones known as androgens to estrogen. After menopause, when the ovaries stop cranking out high levels of estrogen, this hormonal cascade becomes the major source of estrogen in a woman'...
Benign tumors are not life-threatening, do not invade other tissue and they do not spread to other parts of the body. Malignant tumors, on the other hand, can penetrate surrounding tissue and invade nearby organs. They are usually life-threatening. Types of cancer can be broken down into ...
In addition to controlling blood glucose levels, the hormone insulin can stimulate cell growth, possibly leading to cancer. Also, most people with type 2 diabetes are overweight, and their excess fat tissue produces higher levels of adipokines than those at a healthy weight. These hormones promote...
Cachexia is a systemic condition that occurs during many neoplastic diseases, such as cancer. Cachexia in cancer is characterized by loss of body weight and muscle and by adipose tissue wasting and systemic inflammation. Cancer cachexia is often associat
Using a previously characterized model of tumour-promoting mammary CAFs8,9 and patient-derived CAFs isolated from aggressive breast tumours and their matched normal fibroblasts (NFs) isolated from tumour-adjacent tissue, we show that the production of pro-tumorigenic collagens requires increased proline...