(PAFPRS = 0.053,P = 1.9 × 10−3), PRS was the only significant risk factor other than demographic factors. Cancers for which modifiable risk factors had a substantially larger impact on disease burden than PRS included oral cavity/pharynx (PAFmod = 0.310 vs. PAFPRS...
Impact of aspirin on biochemical recurrence of prostate cancer after robot assisted radical prostatectomy in a multicenter retrospective cohort study Shuhei Suzuki ,Hiromitsu Negoro &Takashi Kobayashi Article 15 January 2025|Open Access Application of three statistical approaches to explore effects of dietary...
Journal Rank:Impact Factor 2023: 4.6 - Q1 (ONCOLOGY); CiteScore 2023: 6.6 - Q1 [Pharmacology(medical)] Submission to first decision:63 days Journal Flyer Journalscdr Interview with Prof. David A. Gewirtz: Exploring Breakthroughs in Cancer Drug Resistance and Treatment ...
14. de Thé H. Differentiation therapy revisited. Nat Rev Cancer 2018; 18:117–27. 15. He LZ, Merghoub T, Pandolfi PP. In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications. Oncogene 1999;18:5278–92. 16. Warrell RP,...
We extracted data in terms of scanning year (before and after 2007, 26] and countries (US or not) to explore the impact of scanning year and countries on cancer risks. Scanning year, countries, and continents of studies did not alter cancer risks (Ι2 = 99.61%, P = 0.88;Ι2 =...
As widely recognized, metabolic reprogramming serves as a crucial hallmark of cancer cells, facilitating the establishment of a tumor-promoting microenvironment [64]. Recent studies have shed light on the impact of CAFs on cancer cell metabolism through their intrinsic metabolic reprogramming [24]. How...
5-year Journal Impact Factor 1.4 (2023) Submission to first decision (median) 5 days Downloads 202,065 (2023) Calls for papers Collection Innovations in Early Detection and Treatment of Pancreatic Cancer Pancreatic cancer is a leading cause of cancer-related mortality. ...
Nonstop extension mutations in cancer remain poorly characterized. Here, the authors test the impact of 2335 tumor-derived C-terminal nonstop extensions on protein expression and find the majority to be suppressive; they also analyze their biochemical properties and relation to evolutionary selection pa...
result in both copy number changes and novel interactions between formerly distant genomic elements. This Perspective discusses how the folding of the 3D genome, and differences in its folding across cell types, affect the formation of SVs and their impact on cancer cell fitness in different cancer...
comprising 34 samples from patients who developed distant metastases within a 5-year follow-up period and 44 samples from patients who remained disease-free for at least 5 years after diagnosis. Genomic data were then subjected to biostatistical analysis, followed by the application of the elastic ...