Survey findings showed that 69.8% of oncologists lacked confidence in understanding/interpreting genetic test results, 93.5% expressed the need for assistance in interpreting results, and 64.1% were unable to discuss findings confidently with patients. The most ordered test was BRCA1/2 (47.3%), ...
3 ⅐ No. 2 Genetic testing for breast cancer: Where are health care providers in the decision process? Christine M. Velicer, MS1,2, and Stephen Taplin, MD, MPH2,3 Purpose: To identify BRCA1/2 knowledge, genetic testing intentions, and communication patterns in breast cancer survivors (...
ARTICLE Timing of BRCA1/BRCA2 genetic testing in women with ovarian cancer Molly S. Daniels, MS1, Diana L. Urbauer, MS2, Jennifer L. Stanley, BS1, Kristin G. Johnson, BSN3, and Karen H. Lu, MD1 Purpose: To determine when, in reference to the course of their treatment, women with...
Patients with a higher likelihood to develop BRCA 1 or BRCA 2 mutations are slipping through the cracks, making testing for these mutations a vital part of any breast cancer treatment plan.
Conclusions and Relevance Genetic testing is a powerful tool that allows for the detection of BRCA and non-BRCA germline mutations in individuals with high risks of breast cancer, which in turn aids in the individualization of treatment. Given the magnitude of this disease, it is of great benefi...
Genetic testing Genetic testing can determine whether a person has a specific genetic mutation that can increase the risk of certain diseases or disorders. Genetic tests can detect mutations in theBRCA1andBRCA2genes. Because most breast cancers are not caused by genetic mutations, genetic testing ma...
What happens if you test positive for BRCA gene? Prior to undergoing testing, it is essential that women consider the benefits and risks in light of the possible results. For example, if her test is positive (meaning she is affected by agenetic disorder) there are measures that can reduce ...
Thanks to genetic testing for variants of BRCA1 and BRCA2, “women can be made aware of their risk years ahead of a potential diagnosis,” writes geneticist William Foulkes. He recalls the discovery of the first genes for breast cancer, which have also been strongly associated with ovarian ...
BRCA1/BRCA2genetic testing of women with ovarian cancer has significant implications for both the patients with ovarian cancer and for family members. For the patient, a positive genetic test result indicates an increased risk for primary breast cancer, which may be particularly significant for patie...
Oncologists, internists, and primary care clinicians should be vigilant about offering appropriate genetic testing to males. Identifying more male carriers of BRCA1/2 PVs will maximize opportunities for cancer early detection, targeted risk management, and cancer treatment for males, along with ...