36 Cancer cells divide rapidly,and form growths called tumours(肿瘤). They can spread to take over a whole organ and stop it working properly. If cells break away from the tumour,they can travel to other parts of the body and start new tumours....
Programs, origins and immunomodulatory functions of myeloid cells in glioma A study of myeloid cells in gliomas, a type of brain tumour, used a factor-based computational framework to reveal four immunomodulatory gene-expression programs that are expressed across myeloid cell types, driven by microenvi...
12 Xu, W. et al. METTL3 regulates heterochromatin in mouse embryonic stem cells.Nature, doi:10.1038/s41586-021-03210-1 (2021). 13 Chen, C. et al. Nuclear m(6)A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos.Protein Cell, doi:10.1007/s13...
In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes. Cancer Res. 55, 3369–3373 (1995). CAS PubMed Google Scholar Kershaw, M. H. et al. A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer. Clin. Cancer Res...
Cancer in perspective The Cells of the Body: A History of Somatic Cell Genetics (1995). By Henry Harris. Cold Spring Harbor Laboratory Press. 310 pp. $59. ISBN 0 87969 460 2No abstract is available for this article.doi:10.1002/bies.950180615...
Others inhibit the killing of tumor cell by immune cells. They also can induce the cytokines that inhibit the immune response. Growing tumor cells in a body are surrounded by non-tumor cells. These cells compete with immune cells to bind to the tumor antigens. Due to the insufficient level...
Natural Killer (NK) cells are innate immune cells that play a pivotal role as first line defenders in the anti-tumor response. To prevent tumor development, NK cells are searching for abnormal cells within the body and appear to be key players in immunos
Not all cancer cells can metastasize. In order to spread in this way, the cells must have the ability to penetrate the normal barriers of the body so that they can both enter and exit the blood or lymph vessels. Even traveling metastatic cancer cells face challenges when trying to grow in...
Stage 0 oropharyngeal cancer is confined to the epithelial cells that line the oral cavity or pharynx and is sometimes called carcinoma in situ. Stage I and II cancers are less than 2 cm (about 3/4of an inch) and between 2 and 4 cm, respectively, and have not spread to nearby lymph ...
Jin and his team monitored the spread of the cells and after five weeks, collected samples from the brain, lung, liver, kidney and bone to determine which cell lines took up residence in which organ. The team found that over 200 of the cell lines survived and metastasized in the mice. ...