This is more than an academic question, as the answer will impact approaches to cancer management and prevention. Metabolic studies in a variety of human cancers previously showed that that loss of mitochondrial function preceded the appearance of malignancy and aerobic glycolysis [90]. However, the...
This is more than an academic question, as the answer will impact approaches to cancer management and prevention. Metabolic studies in a variety of human cancers previously showed that that loss of mitochondrial function preceded the appearance of malignancy and aerobic glycolysis [90]. However, the...
“Cancer as a metabolic disease” points the way to this goal.(1) Dr. Seyfried says:“cancer is primarily a metabolic disease involving disturbances in energy production through respiration and fermentation.“(1) Electron microscope studies have shown abnormalities ...
Analysis of large-scale CRISPR screening data, combined with experiments in patient-derived tumour organoid models, identifiesPELOas a potential therapeutic target in chromosomal 9p21.3-deleted cancers and microsatellite-unstable cancers harbouring specific mutations. ...
Aim:The overexpression of Kinesin superfamily proteins (KIFs) has been increasingly recognized as a critical factor associated with unfavorable...MORE Xuewei Zhang, ... Ronghua Yang Open AccessOriginal ArticleDOI:10.20517/2394-4722.2024.9921 Jan 2025 ...
Two recent genome-wide analyses of modular therapies have focused on CAR-T therapy21,22, so we focus first on this technology to put our work in context. In the original formulation, CAR-T therapy used one cell surface target that marks the cells of interest, such as CD19 as a marker ...
ENose: a new frontier for non-invasive cancer detection and monitoring Abstract: Electronic Nose (ENose) technology has emerged as a transformative tool in medical diagnostics, leveraging sensor arrays that mimic the human olfactory system...MORE ...
The understanding of cancer metastasis as a cell autonomous disease of tumor cells has changed in the last decade to being a collective outcome of cancer cells and the acellular and cellular constituents of the tumor microenvironment [1]. Although the genetic and the developmental trajectories of tu...
Researchers have also looked into using metal nanoparticles to identify exosomes, tiny extracellular vesicles released by cancer cells, as a means of early cancer diagnosis. High-sensitivity exosome detection has been achieved by combining gold nanoparticles with surface-enhanced Raman scattering (SERS) ...
This metabolic switch has a variety of beneficial effects on the body, ranging from fat loss to improved brain function. The keto diet could potentially address a number of health conditions, such as obesity, type 2 diabetes, and even cancer. Check out this article for more information on ...