expressing Tie2 (TEMs) can promote tumor angiogenesis by regulating vascular maintenance (cell proliferation, migration, and stabilization) [42]. TEMs express high levels of other proangiogenic factors, such as MMP-9 and VEGF, and M2-polarize (due to increased levels of COX-2, CD206, and WNT...
“It was the right choice for me. I chose a bilateral mastectomy because of my age and not wanting to worry about a recurrence in the same or the other breast,” she said. “I wanted to have peace of mind.” Sumner didn’t need to have radiation after surgery and is now on endocri...
Local chronic inflammation, particularly low-grade inflammation, where macrophages constantly produce low levels of proinflammatory cytokines and reactive oxygen species (ROS), can drive tumor initiation by promoting genomic instability in malignant cells and, at the same time, by interfering with the abi...
discovers and develops transformative T cell therapies (TCR-T) to treat liquid cancers, solid tumors and other serious diseases. Its platform identifies previously uncharacterized, clinically-derived shared T cell antigens and all off-target TCR interactions, to enable the development of efficacious ...
Microplastics in the ocean and other bodies of water have a direct impact on these ecosystems, because the animals that live in these waters are ingesting them. If an animal is at the bottom of the food chain, it can easily spread that plastic up the chain — just as we’re seeing huma...
The other found that having a brother or sister , or a parent with one of several different types of non - melanoma script cancer increased risk as well . Several studies have suggested melanoma and other skin cancers run in families , but it can be difficult to tell t...
Targeted therapies: can sunitinib use be expanded to other cancers?Comment on Ann Oncol. 2011 Dec;22(12):2654-60.doi:10.1038/nrurol.2011.207PaytonSarahNature Reviews Urology
But fear of cancer, a fear that in some cases exceeds the medical evidence, causes great harm all by itself. Doctors, risk experts, and other communicators need to do more to combat this threat by helping the public understand that roughly two-thirds of cancers can now be treated as chroni...
We share the vision that we can make a difference in the protection of women from the devastating consequences of cervical and other lower genital tract ca... We share the vision that we can make a difference in the protection of women from the devastating consequences of cervical and other ...
March 25’s Libra full moon and lunar eclipse sends a seismic wave of energy through your passionate, playfulfifth house. Rather than trying to change other people (a waste of time), focus on adding more fun, uplifting activities to your calendar. Forget about finding a date or dragging a...