genomeresearch ethicsresearch findingsThis paper discusses the nature of genomic information, and the moral arguments in support of an individual's right to access it. It analyses the legal avenues an individual might take to access their sequence information. The authors describe the policy ...
Pindel can detect breakpoints of large deletions, medium sized insertions, inversions, tandem duplications and other structural variants at single-based resolution from next-gen sequence data. It uses a pattern growth approach to identify the breakpoints
reference: /path/to/my/genome.fa neat read-simulator -c neat_config.yml -o simulated_data The output prefix should not specify a file extension (i.e., .fasta, .fastq, etc.), as these will be appended by NEAT. A config file is required. The config is a yml file specifying the inp...
Raw sequences were filtered with a quality score ≥ 29 (a precision of ≥99.87%). Paired-end reads were merged into unique readings using Qiime 1.9.0 [49] to produce consensus sequences and increase the annotation accuracy. Adapters were removed using the Qiime script “split_library.py” ...
Several activities, however, are not common and are carried out by separate EMT- transcription factors (TFs) due to differences in coding sequences or protein size and structure [8]. An overview of the EMT pathway is shown in Figure 1. In other words, EMT is a biotic mechanism in which...
Perhaps the biggest surprise to come from the human genome sequence is the low gene number estimate relative to expectation International Human Genome Sequencing Consortium 2001, Venter et al. 2001. This has now turned the spotlight on posttranscriptional events as a means for generating increased pr...
Complete Genome Sequence of the Endophytic Biocontrol Strain Bacillus velezensis CC09 Bacillus velezensisis a heterotypic synonym ofB. methylotrophicus,B. amyloliquefacienssubsp.plantarum, andBacillus oryzicola, and has been used to control plant fungal diseases. In order to fully understand the genetic ...
On a genetic information front, MyToolbox Genomics keeps your raw genetic information (sequences of nucleotides) but destroys your sample (saliva) as soon as they’re done sequencing. This way, no one else can test or otherwise use your genetic sample. If you don’t want them to have you...
Antibiotic degrading bacteria can reduce the efficacy of drug treatments by providing antibiotic exposure protection to pathogens. While this has been demonstrated at the ecological timescale, it is unclear how exposure protection might alter and be affe
A Whole-genome sequence (WGS) data of n = 507 breast cancers of the International Cancer Genome Consortium (ICGC) were analyzed, of which n = 96 of which were HRD. HRD status was assessed using the CHORD algorithm. B, C Allelic deletions from 507 breast cancers mapping to common...