Under the effect of ferrocene, hydrogen peroxide is split into hydroxyl anions and highly reactive hydroxyl radicals. The latter cause oxidative DNA damage, which induces apoptosis, leading to elimination of cancer cells. Tamoxifen, a drug that interacts with oestrogen receptors, was used as a ...
The ubiquitous cellular labile iron pool (LIP) is often associated with the production of the highly reactive species hydroxyl radical, which forms through redox reaction with hydrogen peroxide. Several studies indicate that LIP-dependent hydroxyl radical production causes cellular damage through oxidation...
acan see clearly the LBP H2O2 oxidation injury prevention activities of intracellular ROS ARPE - 19 cells, reduce the hydrogen peroxide oxidation damage ARPE - 19 cells apoptosis, strength and drug concentration were positively correlated, the description of LBP in ARPE - 19 cells apoptosis has obvi...
Part 3: The role of NOX4 in oxidative damage of diabetic kidney and the intervention mechanism of 1,25(OH)2D3. 报告九 高脂血症通过视网膜内皮细胞IRE1α-XBP1激活STING通路诱导促炎反应 Zheyao Wen 中山大学附属第三医院 报...
10. Melatonin exerts a direct antioxidant effect on tissues/organs and antiapoptotic effects on cells. Melatonin inhibits neutrophil activation and reduces the damage they cause to endothelial cells, which is thought to occur in Covid-19 patients. ...
The bound MPO also retains its enzymic functions and effectively interacts with hydrogen peroxide to mediate detachment of endothelial cells from their substratum. EC bound MPO-anti-MPO complexes can contribute to the complement-dependent EC injury demonstrated by some P-ANCA sera....
Hydrogen peroxide is a damage signal at sites of chronic inflammation. The question arises whether platelet-rich fibrin (PRF), platelet-poor plasma (PPP), and the buffy coat can neutralize hydrogen peroxide toxicity and thereby counteract local oxidative stress. In the present study, gingival fibrob...
The RpoS regulon allows cells to survive a variety of environmental stresses, for instance oxidative stress26,30,47. To test the function of heterogeneous RpoS expression, we assayed the survival of exponential phase cells against hydrogen peroxide (H2O2). We used a short, intense pulse of stress...
Additionally, the accumulation of hydrogen peroxide in the hair shaft during aging is also thought to lead to hair shaft bleaching, she adds. "To counteract this, an enzyme known as 'catalase' can help break down hydrogen peroxide, which could theoretically slow down graying," Dr. Shaver expla...
reduce the hydrogen peroxide oxidation damage ARP 由Hochest弄脏和流程cytometry,分别从细胞形态学、ROS的细胞活动和线粒体膜潜力变动和细胞apoptosis,能清楚地看细胞内ROS ARPE - 19个细胞的LBP水2氧化作用伤害预防活动,减少过氧化氢氧化作用损伤ARPE - 19个细胞apoptosis、力量和药物集中在ARPE正面地被关联了, LBP...