Domain V is the major cell-binding domain and is potentially a very interactive molecule since it is organized in a structure similar to that of agrin and various types of laminin, and it also binds heparin and α-dystroglycan among other molecules (36, 37). Thus, we employed this fragment...
Patients who underwent major bariatric procedures received subcutaneous low molecular weight heparin as perioperative venous thromboembolism prophylaxis, subsequently switching to rivaroxaban for 30 consecutive days, beginning on the postoperative fourth day. DNA Purification Using the Caprini score's evaluation ...
In the present study, we show that vascular endothelial cells are the primary cellular target of sorafenib-induced HFSR wherein soluble heparin-binding epidermal growth factor (s-HBEGF) mediates the crosstalk between vascular endothelial cells and keratinocytes. Mechanistically, s-HBEGF released from ...
no patient had a blood pH lower than 7.4, which seems to be a critical point for both BK release20and, from our in vitro experiments, for NOS activation. Since the electronegative charge of membranes could be a major factor in BK activation, heparin (highly negatively charged molecule)29was...