Better than those spoiled college brats who drown their brain cells in booze everyday. KI-WOO That may be true but-- You think the family would accept me? I’m not even a college student. 11. the picture again. MIN-HYUK We’ll embellish a little. You’ll be fine. You’ll ...
Although it has been reported that bone marrow-derived cells (BMDCs) can transdifferentiate into neural cells, the findings are considered unlikely. It has been argued that the rapid neural transdifferentiation of BMDCs reported in culture studies is actually due to cytotoxic changes induced by the ...
Primary human hepatocytes (PHH) and Hepatic stellate cells (HSC) were co-cultured to produce cell sheets, which were cultured in glucose and lipid containing medium, following which histological and functional analyses were performed. Histological findings showed hepatocyte ballooning, accumulation of ...
Analysis of an antigen-specific, H-2-restricted cell-free product(s) made by "I-J−" Ly-2 cells (Ly-2 TsF) that suppresses Ly-2 cell-depleted spleen cell activity Immune Ly-1鈭,2+ splenic T cells release material(s) (Ly-2 TsF) into culture supernatants which (a) are antigen-sp...
Cells were centrifuged at 4 °C and washed five times with 1×PBS. The pellet was resuspended in RIPA buffer (SDS, 0.1%; sodium deoxycholate, 0.5%; Triton X-100, 0.5%; 1 mM; NaCl, 150 mM; Tris, pH 8, 50 mM; Proteases Inhibitor-Complete, Mini, ethylenediaminetetraacetic ...
As TM α-helices, WALP peptides of different length as well as the TM domains of the syntaxin-1A and of the linker for activation of T cells (LAT) proteins were used. Free energy calculations revealed that the enthalpic contribution due to the tight packing of the lipids in lo drives TM...
British scientists believe they may have found a way to fight the common cold. It blocks a key protein in the body’s cells that is to1for the spread of cold-causing virus. Targeting the host rather than the infection was a bit non-traditional but made sense because it was tricky to ...
Scientists have succeeded in producing cartilage formed from embryonic stem cells that could in future be used to treat the painful joint condition osteoarthritis. In research funded by Arthritis Research UK, Professor Sue Kimber and her team in the Faculty of Life Sciences at The University of Man...
To investigate whether BRCA2-independent SCEs can be observed in other cell lines, we introduced shRNAs targeting BRCA2 in untransformed human TP53-/- RPE-1 cells (Fig. 2A). We observed a loss of irradiation-induced RAD51 foci in BRCA2-depleted TP53-/- RPE1 cells (Supplementary Fig. 2A)...
structure5and function in cells, may lead to refinement of the protein homeostasis model6of proteome maintenance, are likely to be relevant to how synonymous mutations have long-term impacts on protein structure and function7, and could reveal long-term misfolding on a scale greater than ...