Podocytes, which are specialized epithelial cells located in the glomerulus, are an important part to maintain the charge barrier function together with vascular endothelial cells (ECs) [56]. Research has indicated that hyperglycemia has the potential to induce podocyte apoptosis, resulting in proteinuri...
Hippocampal place cells contribute to mammalian spatial navigation and memory formation. Numerous models have been proposed to explain the location-specific firing of this cognitive representation, but the pattern of excitatory synaptic input leading to
10 as a function of indentation velocity together with the results of the wet cells, already shown in Fig. 8. Compared to the wet cells the dry cells do not only exhibit a higher force level, they also show a higher dynamic change. In fact the force maximum of the dry cells increases...
In my pursuit to determine why I still cannot add any new foods to my extremely limited diet (I’m currently only eating four organic foods), I’ve come across a cellular issue called Cell Danger Response (CDR) that is beginning to make sense as a cause of my very narrow diet. I fir...
Studies regarding the importance of CadF for adhesion to the host cell come to different conclusions. On the one hand, recent studies show that CadF is not an essential factor for infection of mice and the absence of CadF in correspondingCampylobactermutants hardly influences the resulting infecti...
Indeed, within the notum anlage, cells not expressing Iro-C tend to join together and sort out from their Iro-C expressing neighbours. We also show that apposition of Iro-C expressing and non-expressing cells induces invagination and apico-basal shortening of the Iro-C- cells. This effect ...
to calculate the signature score across these 26 clones derived from the whole BMNCs, and found only a small fraction of CFUs were inferred to come from the above two stem cell populations (Fig.5d, e). Indeed, genuine single stem cell within the BM could form clone, but the reverse ...
Taken together, both biophysical analysis of FX binding to Hexon by SPR measurements and biological assays analyzing FX-mediated SKOV-3 transduction confirmed that FX binding to HAdV-5-HexPos3 was not inhibited. Unexpectedly, in the absence of FX, HAdV-5-HexPos3-Δ5FX showed enhanced ...
Aging impacts diseases and lifespan. With current knowledge of stem cells, it is feasible to design and test interventions that delay aging and improve both health and lifespan. Stem cells, together with anti-aging genes such as Klotho, play a crucial ro
Taken together with the analysis of G1 phase (Fig. 4), these results show that modulation of G1 and/or S-G2 duration contributes to size control in cells that on average grow exponentially but that the two cell types we studied rely differently on these mechanisms in order to achieve a...